前庭康复训练对周围性眩晕患者临床疗效及血流动力学指标的影响  

Effect of vestibular rehabilitation training on the clinical efficacy and hemodynamic indexes in patients with peripheral vertigo

作　　者：赵蕾[1] 史林娟 刘磊 宋红娜 任翠玲 段佩养 Zhao Lei;Shi Linjuan;Liu Lei;Song Hongna;Ren Cuiling;Duan Peiyang(The Second Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China)

机构地区：[1]河南科技大学第二附属医院,河南洛阳471000

出　　处：《临床心身疾病杂志》2024年第6期20-24,共5页Journal of Clinical Psychosomatic Diseases

基　　金：河南省医学科技攻关计划联合共建项目(编号LHGJ20191249)。

摘　　要：目的探究前庭康复训练联合倍他司汀和银杏叶提取物片对周围性眩晕患者临床疗效及血流动力学指标的影响。方法将104例周围性眩晕患者按随机数字表法分为研究组52例与对照组52例,对照组患者给予耳石复位法治疗,并给予倍他司汀和银杏叶提取物片,研究组患者在对照组基础上给予前庭康复训练,两组患者均治疗4周。治疗前后,比较两组患者临床疗效、眩晕残障程度评定量表(DHI)评分、眩晕症状评分简化量表(VSS-SF)评分、Berg平衡量表(BBS)评分、血流动力学指标[血细胞比容(HCT)、全血黏度(BV)及基底动脉(BA)、左椎动脉(LVA)和右椎动脉(RVA)处收缩期峰值血流速度(PSV)和舒张期末血流速度(EDV)]及随访期间疾病复发情况。结果治疗后,研究组患者临床疗效总有效率高于对照组(P<0.05)。治疗后,两组患者DHI、VSS-SF评分均较治疗前降低,且研究组低于对照组(P<0.01);治疗后,两组患者BBS评分均较治疗前升高,且研究组高于对照组(P<0.01)。治疗后,两组患者HCT、BV水平均较治疗前降低,且研究组低于对照组(P<0.01);治疗后,两组患者PSV(BA、RVA、LVA)、EDV(BA、RVA、LVA)均较治疗前升高,且研究组高于对照组(P<0.01)。两组患者均无失访情况,研究组患者复发6例(11.54%),对照组患者复发14例(26.92%),研究组患者复发率低于对照组,(P<0.05)。结论前庭康复训练联合倍他司汀和银杏叶提取物片治疗周围性眩晕患者效果理想,能够明显改善患者眩晕症状,调节血流动力学指标,有效降低复发风险,值得临床参考借鉴。Objective To explore the effects of vestibular rehabilitation training plus betahistine and ginkgo biloba extract tablets(GBET)on the clinical efficacy and hemodynamic indexes of patients with peripheral vertigo(PV).Methods A total of 104 PV patients were divided into research(n=52)and control group(n=52)according to random number table method.Controls received the treatment of otolith repositioning maneuver,betahistine and GBET,research group did vestibular rehabilitation training on the basis of controls for 4 weeks.Such indexes were compared between two groups as clinical efficacy,Dizziness Handicap Inventory(DHI),Vertigo Symptom Scale-Short Form(VSSSF)and Berg Balance Scale(BBS)score,hemodynamic indicators(hematocrit[HCT]and whole blood viscosity[BV]as well as the peak systolic velocity[PSV]and end-diastolic velocity[EDV]in the basilar artery[BA],left vertebral artery[LVA],and right vertebral artery[RVA]),and recurrence during follow-up.Results After treatment total effective rate was higher in research than control group(P<0.05).After treatment,scores on the DHI and VSS-SF lowered in both groups compared with pre-treatment and those were lower in the research than control group(P<0.01);scores on the BBS elevated in both groups and that was higher in research group than controls(P<0.01).After treatment,the HCT and BV levels lowered in both groups compared with pre-treatment and those were lower in research group than controls(P<0.01);the PSV and EDV in the BA,RVA,and LVA elevated in both groups and those were higher in research group than controls(P<0.01).No patients were lost to follow up in both groups,6 ones(11.54%)relapsed in research group,14 ones(26.92%)did in controls,and the relapse rate was lower in research group than controls(P<0.05).Conclusion Vestibular rehabilitation training plus betastatin and the GBET is ideal for the treatment of PV patients,could obviously improve vertigo symptoms,regulate hemodynamic indicators,lower relapse risk effectively,and deserves clinical reference.

关 键 词：周围性眩晕 前庭康复训练 倍他司汀 血流动力学 

分 类 号：R441.2[医药卫生—诊断学]