良性前列腺增生伴夜尿症患者术后睡眠质量及与负性情绪的相关性分析  

Postoperative sleep quality and its correlation with negative emotions in patients with benign prostatic hyperplasia complicated by nocturia

作　　者：叶纪伟[1] 穆克飞 李林波 刘凯[2] Ye Jiwei;Mu Kefei;Li Linbo;Liu Kai(Nanyang Second People's Hospital,Nanyang 473000,Henan,China;不详)

机构地区：[1]南阳市第二人民医院,河南南阳473000 [2]郑州大学第五附属医院,河南郑州450000

出　　处：《临床心身疾病杂志》2024年第6期57-61,共5页Journal of Clinical Psychosomatic Diseases

基　　金：河南省医学科技攻关计划联合共建项目(编号LHGJ20190421)。

摘　　要：目的探讨良性前列腺增生(BPH)伴夜尿症患者术后睡眠质量及与负性情绪的相关性。方法选取103例BPH伴夜尿症患者为研究对象,所有患者均实施经尿道前列腺切除术(TURP)。收集患者相关临床资料;采用国际前列腺症状评分(IPSS)评估患者症状严重程度,采用匹兹堡睡眠质量指数(PSQI)评估患者睡眠质量,并根据术后PSQI评分将患者分为睡眠正常组69例(PSQI总分<5.5分)与睡眠障碍组34例(PSQI总分≥5.5分);采用汉密顿焦虑量表(HAMA)与汉密顿抑郁量表(HAMD)评估患者焦虑与抑郁负性情绪;应用Spearman相关性分析评估患者睡眠质量与负性情绪的相关性,采用Logistic回归分析探讨患者TURP术后睡眠障碍的影响因素,绘制受试者工作特征(ROC)曲线,以曲线下面积(AUC)评估负性情绪对患者TURP术后睡眠质量的预测效能。结果术后患者PSQI总分及各维度评分、HAMA评分、HAMD评分均低于术前(P<0.01)。术后睡眠障碍组患者IPSS评分、HAMA评分、HAMD评分均高于睡眠正常组(P<0.01)。术后患者PSQI评分与HAMA评分、HAMD评分、IPSS评分均呈正相关(P<0.01)。多因素Logistic回归分析结果显示,HAMA评分、HAMD评分是术后患者睡眠质量出现障碍的危险因素(P<0.01)。ROC曲线分析结果显示,HAMA评分、HAMD评分及两者联合对患者术后睡眠障碍预测的AUC分别为0.837、0.788、0.904。结论BPH伴夜尿症患者TURP术后睡眠质量提高,负性情绪得到改善。HAMA评分、HAMD评分两者联合对患者TURP术后睡眠质量的预测效能较高。Objective To explore the postoperative sleep quality and its correlation with negative emotions in patients with benign prostatic hyperplasia(BPH)complicated by nocturia.Methods A total of 103BPH patients with nocturia were selected as research objects and they all had undergone transurethral resection of prostate(TURP).Patient-related clinical data were collected.The severity of symptoms was assessed with the International Prostate Symptom Score(IPSS).Sleep qualities were assessed with the Pittsburgh Sleep Quality Index(PSQI)and they were divided into normal-sleep(n=69,the total score of the PSQI<5.5)and sleep disorder(n=34,the total score of the PSQI≥5.5).Anxious and depressive emotions were assessed with Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD).The correlation between sleep quality and negative emotions was assessed using Spearman correlation analysis,influencing factors of postoperative sleep disorders were explored using Logistic regression analysis,receiver operating characteristic curve(ROC)was plotted and the area under the curve(AUC)used to evaluate the predictive efficacy of negative emotions for sleep quality after the TURP.Results After operation the total and each dimension score of the PSQI as well as HAMA and HAMD score of the patients were lower compared with pre-operation(P<0.01).The IPSS,HAMA and HAMD score were higher in sleep disorder than normal-sleep group(P<0.01).Postoperative PSQI score was positively correlated with HAMA,HAMD and IPSS score(P<0.01).Multivariate Logistic regression analysis showed that the HAMA and HAMD score were risk factors for the occurrence of post-operative sleep disorders(P<0.01).The ROC analysis showed that the AUC of HAMA and HAMD score as well as their combination for predicting postoperative sleep disorders was 0.837,0.788 and 0.904,respectively.Conclusion The sleep quality and negative emotions of BPH patients with nocturia after TURP are improved.The combination of HAMA score and HAMD score has higher predicting efficacy in sleep quali

关 键 词：夜尿症 良性前列腺增生 经尿道前列腺切除术 睡眠质量 负性情绪 

分 类 号：R697.3[医药卫生—泌尿科学]