针刺联合药罐疗法治疗慢性阻塞性肺疾病急性加重期临床研究  

Clinical Study on Combination Use of Acupuncture and Drug Cupping Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease

作　　者：温建武 麻献秋 俞亦好 徐志微 WEN Jianwu;MA Xianqiu;YU Yihao;XU Zhiwei(Wenzhou Central Hospital,Wenzhou Zhejiang 325400,China)

机构地区：[1]温州市中心医院,浙江温州325400

出　　处：《新中医》2024年第21期119-123,共5页New Chinese Medicine

基　　金：温州市科研项目(Y20210458)。

摘　　要：目的:观察针刺联合药罐疗法治疗慢性阻塞性肺疾病急性加重期疗效。方法:选取86例慢性阻塞性肺疾病急性加重期患者,按随机数字表法分为对照组、研究组各43例,对照组给予常规现代医学治疗,研究组在对照组基础上给予针刺联合药罐疗法治疗。比较2组临床疗效,比较2组治疗前后中医证候评分、肺功能指标值[用力肺活量(FVC)、第1秒用力呼气量(FEV_(1))、第1秒用力呼气量/用力肺活量(FEV_(1)/FVC)]、血气参数[动脉血氧分压(PaO_(2))、二氧化碳分压(PaCO_(2))、酸碱度(pH)、血氧饱和度(SaO_(2))]、炎症因子[C-反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)]水平的变化。结果:研究组临床疗效总有效率为97.67%,对照组为83.72%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组咳嗽喘息、咳痰、发热口干、心悸、大便干结中医证候积分均较治疗前下降(P<0.05),研究组上述5项中医证候积分均低于对照组(P<0.05)。治疗后,2组FVC、FEV_(1)、FEV_(1)/FVC水平均较治疗前上升(P<0.05),研究组上述3项水平均高于对照组(P<0.05)。治疗后,2组PaO_(2)、pH、SaO_(2)参数值均较治疗前上升(P<0.05),PaCO_(2)参数均较治疗前下降(P<0.05);研究组PaO_(2)、pH、SaO_(2)参数值均高于对照组(P<0.05),PaCO_(2)参数低于对照组(P<0.05)。治疗后,2组CRP、IL-6、IL-1β水平均较治疗前下降(P<0.05),研究组上述3项炎症因子水平均低于对照组(P<0.05)。结论:针刺联合药罐疗法治疗慢性阻塞性肺疾病急性加重期临床效果较好,能有效缓解临床症状,降低炎症因子水平,提高肺功能,改善血气指标。Objective:To observe the curative effect of the combination use of acupuncture and drug cupping therapy on acute exacerbation of chronic obstructive pulmonary disease.Methods:A total of 86 patients with acute exacerbation of chronic obstructive pulmonary disease were selected and divided into the control group and the study group according to the random number table method,with 43 cases in each group.The control group was given routine modern medical treatment,and the study group was additionally given acupuncture combined with drug cupping therapy based on the treatment of the control group.The clinical effects,and the changes of traditional Chinese medicine syndrome scores,and levels of pulmonary function indexes[forced vital capacity(FVC),forced expiratory volume in one second(FEV_(1)),and FEV_(1)/FVC],blood gas parameters[partial pressure of oxygen in arterial blood(PaO_(2)),partial pressure of carbon dioxide(PaCO_(2)),pondus hydrogenii(pH),oxygen saturation in arterial blood(SaO_(2))],and of inflammatory factors[C-reactive protein(CRP),interleukin-6(IL-6),interleukin-1β(IL-1β)]before and after treatment were compared between the two groups.Results:The total effective rate was 97.67%in the study group and 83.72%in the control group,the difference being significant(P<0.05).After treatment,the traditional Chinese medicine syndrome scores of cough and wheezing,expectoration,fever and dry mouth,and palpitation and dry stool in the two groups were decreased when compared with those before treatment(P<0.05),and the above five scores in the study group were lower than those in the control group(P<0.05).After treatment,the levels of FVC,FEV_(1)and FEV_(1)/FVC in the two groups were increased when compared with those before treatment(P<0.05),and the above three levels in the study group were higher than those in the control group(P<0.05).After treatment,the values of PaO_(2),pH and SaO_(2)in the two groups were elevated when compared with those before treatment(P<0.05),and the PaCO_(2)values were reduced when compar

关 键 词：慢性阻塞性肺疾病 急性加重期 针刺 药罐疗法 炎症因子 肺功能 

分 类 号：R563[医药卫生—呼吸系统]