茯苓桂枝白术汤加减治疗气虚血瘀型冠心病的效果  

Effect of Modified Fuling Guizhi Baizhu Dection in Treating Coronary Heart Disease of Qi Deficiency and Blood Stasis Type

作　　者：杨艳霞 邓国涛 YANG Yanxia;DENG Guotao(Pharmacy of Traditional Chinese Medicine,Leling Hospital of Traditional Chinese Medicine,Dezhou 253600,Shandong,China;Department of Traditional Chinese Medicine,Leling Hospital of Traditional Chinese Medicine,Dezhou 253600,Shandong,China)

机构地区：[1]乐陵市中医院中药房,山东德州253600 [2]乐陵市中医院中医科,山东德州253600

出　　处：《世界复合医学（中英文）》2024年第7期33-37,共5页World Journal of Complex Medicine

摘　　要：目的评估茯苓桂枝白术汤加减治疗气虚血瘀型冠状动脉粥样硬化性心脏病(简称冠心病)的效果。方法回顾性选取2019年1月—2022年12月乐陵市中医院收治的124例冠心病患者的临床资料,根据治疗方法不同分为两组,每组62例。对照组接受常规西药治疗,研究组给予常规西药联合茯苓桂枝白术汤加减治疗。比较两组心功能指标、血脂水平、血液流变学指标、中医证候积分。结果治疗后,研究组左室射血分数为(46.03±4.25)%,高于对照组的(40.68±4.17)%,差异有统计学意义(t=7.075,P<0.05)。治疗后,研究组左心室收缩末期内径、左心室舒张末期内径低于对照组,差异有统计学意义(P均<0.05)。研究组高密度脂蛋白胆固醇水平高于对照组,低密度脂蛋白胆固醇、甘油三酯、总胆固醇水平低于对照组,差异有统计学意义(P均<0.05)。研究组高切全血黏度、低切全血黏度、血浆黏度、纤维蛋白原水平均低于对照组,差异有统计学意义(P均<0.05)。研究组中医医证候积分低于对照组,差异有统计学意义(P均<0.05)。结论将常规西药联合茯苓桂枝白术汤加减治疗方法应用到气虚血瘀型冠心病患者中,有利于改善患者心功能、血脂、血液流变学情况,降低中医证候积分。Objective To evaluate the effect of modified Fuling Guizhi Baizhu Decoction in treating coronary heart disease with qi deficiency and blood stasis type.Methods Clinical data of 124 patients with coronary heart disease treated in Leling Hospital of Traditional Chinese Medicine from January 2019 to December 2022 were retrospectively selected and divided into two groups according to different treatment methods,with 62 cases in each group.The control group received conventional Western medicine treatment,and the study group received conventional Western medicine combined with modified Fuling Guizhi Baizhu Decoction.The indexes of cardiac function,lipid levels,hemorheology and traditional Chinese medicine syndrome score were compared between the two groups.Results After treatment,the left ventricular ejection fraction of the study group was(46.03±4.25)%,which was higher than(40.68±4.17)%of the control group,and the difference was statistically significant(t=7.075,P<0.05).After treatment,the left ventricular end-systolic dimension and left ventricular end-diastolic dimension in the study group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The level of high-density lipoprotein cholesterol in the study group was higher than that in the control group,and the levels of low-density lipoprotein cholesterol,triglyceride and total cholesterol were lower than those in the control group,the differences were statistically significant(all P<0.05).The levels of high shear whole blood viscosity,low shear whole blood viscosity,plasma viscosity and fibrinogen in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The traditional Chinese medicine syndrome scores of the study group were lower than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion Applying the routine Western medicine combined with modified Fuling Guizhi Baizhu Decoction to the patients wit

关 键 词：茯苓桂枝白术汤 气虚血瘀型 冠心病 

分 类 号：R4[医药卫生—临床医学]