督灸联合加味参芪地黄汤治疗前列腺癌骨转移的临床疗效评价  

Evaluation of the Clinical Efficacy of Du Moxibustion Combined with Modified Shenqi Dihuang Decoction in the Treatment of Bone Metastasis of Prostate Cancer

作　　者：高伟 刘中华[2] 李倩 葛南[3] GAO Wei;LIU Zhonghua;LI Qian;GE Nan(Department of Urology,Jinxiang County People's Hospital,Jining 272200,Shandong,China;Department of Traditional Chinese Medicine,Jinxiang County People's Hospital,Jining 272200,Shandong,China;Department of Urology,Second Hospital of Shandong University,Jinan 250012,Shandong,China)

机构地区：[1]金乡县人民医院泌尿外科,山东济宁272200 [2]金乡县人民医院中医科,山东济宁272200 [3]山东大学第二医院泌尿外科,山东济南250012

出　　处：《系统医学》2024年第18期1-4,8,共5页Systems Medicine

基　　金：山东省中医药科技项目(M-2023344)。

摘　　要：目的分析督灸联合加味参芪地黄汤治疗前列腺癌骨转移的临床疗效。方法非随机选取2020年3月—2023年6月金乡县人民医院收治的62例前列腺癌骨转移患者作为研究对象,按治疗方法不同分为对照组和治疗组,各31例。对照组接受单纯加味参芪地黄汤治疗,治疗组接受督灸联合加味参芪地黄汤治疗。对比两组患者临床疗效、骨转移情况以及生存质量。结果治疗组治疗有效率为90.32%(28/31),高于对照组的80.65%(25/31),差异有统计学意义(χ^(2)=4.769,P<0.05);治疗组碱性磷酸酶水平为(137.24±10.23)U/L,低于对照组的(172.95±10.64)U/L,治疗组疼痛数字水平为(3.75±1.86)分,低于对照组的(4.91±2.57)分,差异有统计学意义(t=13.470、2.035,P均<0.05);治疗组卡氏功能状态评分为(80.42±11.44)分,高于对照组的(71.59±11.28)分,治疗组体能状态评分为(1.01±0.11)分,低于对照组(1.89±0.99)分,差异有统计学意义(t=3.060、4.918,P均<0.05)。结论前列腺癌骨转移患者应用督灸联合加味参芪地黄汤进行治疗可获得良好效果,不仅能够有效提升患者治疗有效率及生存质量,还可在一定程度上改善其骨转移症状。Objective To analyze the clinical efficacy of Du moxibustion combined with modified Shenqi Dihuang decoction in the treatment of bone metastasis of prostate cancer.Methods Sixty-two patients with bone metastasis of prostate cancer admitted to Jinxiang County People's Hospital from March 2020 to June 2023 were non-randomly selected as the study subjects.They were divided into control group and treatment group according to different treatment methods,with thirty-one cases in each group.The control group was treated with modified Shenqi Dihuang Decoction alone,and the treatment group was treated with Du moxibustion combined with modified Shenqi Dihuang Decoction.The clinical efficacy,bone metastasis and quality of life were compared between the two groups.Results The effective rate of the treatment group was 90.32%(28/31),which was higher than 80.65%(25/31)of the control group,and the difference was statistically significant(χ^(2)=4.769,P<0.05).In the treatment group,the alkaline phosphatase level was(137.24±10.23)U/L,which was lower than that of the control group(172.95±10.64)U/L,the pain digital score of the treatment group was 3.75±1.86,which was lower than that of the control group 4.91±2.57,the differences were statistically significant(t=13.470,2.035,both P<0.05);In the treatment group,the Karnofsky functional status score was 80.42±11.44,which was higher than that of the control group 71.59±11.28,the physical status score of the treatment group was 1.01±0.11,which was lower than that of the control group 1.89±0.99,the difference was statistically significant(t=3.060,4.918,both P<0.05).Conclusion The application of Du moxibustion combined with modified Shenqi Dihuang decoction in patients with bone metastasis of prostate cancer can achieve good results,which can not only effectively improve the treatment efficiency and quality of life of patients,but also improve the symptoms of bone metastasis to a certain extent.

关 键 词：前列腺癌 骨转移 督炙 加味参芪地黄汤 

分 类 号：R69[医药卫生—泌尿科学]