注射用乳糖酸红霉素联合布地奈德治疗支气管肺炎合并肺炎支原体感染的临床价值研究  

Clinical Value of Erythromycin Lactobionate for Injection Combined with Budesonide in the Treatment of Bronchial Pneumonia Complicated with Mycoplasma Pneumoniae Infection

作　　者：仇宝玲 徐健 戴俊杰 QIU Baoling;XU Jian;DAI Junjie(Department of Pediatrics,Children's Hospital of Fudan University Qidong Branch(Qidong Maternal and Child Health Hospital),Qidong 226200,Jiangsu,China)

机构地区：[1]复旦大学附属儿科医院启东分院(启东市妇幼保健院)儿内科,江苏启东226200

出　　处：《系统医学》2024年第18期137-139,150,共4页Systems Medicine

摘　　要：目的研究注射用乳糖酸红霉素联合布地奈德在支气管肺炎合并支原体感染治疗中的效果。方法非随机选取2022年6月—2023年7月复旦大学附属儿科医院启东分院(启东市妇幼保健院)收治的109例支气管肺炎合并支原体感染患儿作为研究对象,根据治疗药物不同将患者分为对照组和研究组,对照组54例,研究组55例。对照组给予乳糖酸红霉素治疗,研究组采用注射用乳糖酸红霉素联合布地奈德治疗。对比两组症状消失时间、临床疗效、不良反应发生情况。结果治疗后,研究组各项症状的消失时间均短于对照组,差异有统计学意义(P均<0.05);研究组治疗总有效率为96.36%(53/55),高于对照组的83.33%(45/54),差异有统计学意义(χ^(2)=5.099,P<0.05);研究组不良反应发生率为10.91%(6/55),低于对照组的14.81%(8/54),差异无统计学意义(χ^(2)=0.371,P>0.05)。结论注射用乳糖酸红霉素与布地奈德联合应用于支气管肺炎合并肺炎支原体感染的治疗中,能够缩短症状消失时间,提高临床疗效,且安全性较高。Objective To study the effect of erythromycin lactobionate for injection combined with budesonide in the treatment of bronchial pneumonia complicated with mycoplasma infection.Methods From June 2022 to July 2023,109 patients with bronchial pneumonia complicated with mycoplasma infection admitted to Qidong Branch of Children's Hospital of Fudan University(Qidong Maternal and Child Health Hospital)were non-randomly selected as the research objects.According to different therapeutic drugs,the patients were divided into control group and study group,with 54 cases in the control group and 55 cases in the study group.The control group was treated with erythromycin lactobionate,and the study group was treated with erythromycin lactobionate for injection combined with budesonide.The disappearance time of symptoms,clinical efficacy and adverse reactions were compared between the two groups.Results After treatment,the disappearance time of each symptom in the study group was shorter than that in the control group,and the difference were statistically significant(all P<0.05).The total effective rate of treatment in the study group was 96.36%(53/55)higher than 83.33%(45/54)in the control group,and the difference was statistically significant(χ^(2)=5.099,P<0.05).The research group had lower incidence of adverse reactions as 10.91%(6/55)than 14.81%(8/54)in the control group,and the difference was not statistically significant(χ^(2)=0.371,P>0.05).Conclusion The combination of erythromycin lactobionate for injection and budesonide in the treatment of bronchial pneumonia complicated with mycoplasma pneumoniae infection can shorten the time of symptom disappearance,improve the clinical efficacy,and has high safety.

关 键 词：乳糖酸红霉素 布地奈德 支气管肺炎 肺炎支原体感染 临床疗效 症状消失 不良反应 

分 类 号：R72[医药卫生—儿科]