藏药西藏凹乳芹及其近似种的数字化生药学研究  

Digitized Pharmacognostical Study of Vicatia thibetica de Boiss and Its Similar Species

作　　者：王艺娱 高必兴 齐景梁 李倩 苟琰 高驰 王颖 兰志琼[2] WANG Yiyu;GAO Bixing;QI Jingliang;LI Qian;GOU Yan;GAO Chi;WANG Ying;LAN Zhiqiong(NMPA Key Laboratory of Quality Evaluation of Chinese Patent Medicines,Sichuan Institute for Drug Control,Chengdu 611731,China;MOE Key Laboratory of Standardization of Chinese Herbal Medicine,State Key Laboratory of Traditional Chinese Medicine Resources of Southwestern China,College of Modern Chinese Medicine Industry,College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China)

机构地区：[1]四川省药品检验研究院,国家药品监督管理局中成药质量评价重点实验室,成都611731 [2]成都中医药大学药学院,现代中药产业学院,中药材标准化教育部重点实验室,西南特色中药资源国家重点实验室,成都611137

出　　处：《中国药学杂志》2024年第18期1705-1714,共10页Chinese Pharmaceutical Journal

基　　金：四川省中医药管理局科研项目资助(2024MS521)。

摘　　要：目的建立藏药西藏凹乳芹与其近似品种的生药学鉴别及数字化表征方法。方法采集西藏凹乳芹及其近似种的原植物并制作腊叶标本,使用数码相机、体式显微镜、光学显微镜及数码成像技术对其原植物、药材性状、根横切面及粉末显微鉴别进行生药学研究与数字化表征。结果建立了西藏凹乳芹及7个近似品种(迷果芹、西藏棱子芹、东当归、松潘棱子芹、羽苞藁本、裂叶独活、峨参)的植物、药材性状及显微鉴别分类检索表,发现各品种间植物的主要区别在于花及果实;药材性状的主要区别在根头部、表面及断面特征;显微的主要区别在于分泌组织类型及是否有后含物等。结论所建立的分类检索表能有效鉴别西藏凹乳芹及其近似种,为其品种分类及临床使用提供科学依据,以及智能识别技术在藏药鉴别上的应用探索奠定基础,也为中药数字标本平台提供资料。OBJECTIVE To establish a method for the pharmacognostic identification and digital characterization of the Vicatia thibetica de Boiss and its similar species.METHODS The original plant specimens of Vicatia thibetica de Boiss.and its similar species,and carried out pharmacognostic studies and digital characterization of morphologic characteristics,character identification,microscopic identification using digital camera,body microscope,light microscope,and digital imaging systems were collected and made.RESULTS Taxonomic checklists of morphologic characteristics,character identification and microscopic identification were established for the Vicatia thibetica de Boiss and 7 similar varieties[Sphallerocarpus gracilis(Bess.)K.-Pol.,Pleurospermum hookeri var.thomsonii C.B.Clarke,Angelica acutiloba(Sieb.et Zucc.)Kitagawa,Pleurospermum franchetianum Hemsl.,Ligusticum daucoides(Franch.)Franch.,Heracleum millefolium Diels,Anthriscus sylvestris(L)Hoffm.],and it was found that the main differences between the 8 plants were in the flowers and fruits,and that the main differences in character identification were in the characteristics of the root heads,surfaces,and cross-sections,and that the main differences in the microscopic identifications were in the types of secretory tissues and the presence or absence of posterior inclusions,etc.CONCLUSION The established taxonomic checklists can effectively identify Vicatia thibetica de Boiss and its similar species,and provide a scientific basis for its species classification and clinical use.It also lays a foundation for the exploration of the application of intelligent identification technology in the identification of Tibetan medicines,and provides information for the platform of digital specimens of traditional Chinese medicine.

关 键 词：西藏凹乳芹 加哇 生药学 数字化 基原鉴定 药材性状 显微鉴别 

分 类 号：R282[医药卫生—中药学]