体外膈肌起搏器治疗肺病急性加重期效果研究  

Study on the effect of external diaphragm pacer in the treatment of acute exacerbation of pulmonary diseases

作　　者：杨格 陈伟 祝旺 史为涛 刘帅 李涛 赵程 YANG Ge;CHEN Wei;ZHU Wang;SHI Weitao;LIU Shuai;LI Tao;ZHAO Cheng(Department of Cardiology,Xuzhou City Hospital Affiliated to Xuzhou Medical University,Xuzhou 221000,China;Xuzhou Clinical College,Xuzhou Medical University,Xuzhou 221000,China;Department of Critical Care Medicine,Xuzhou City Hospital Affiliated to Xuzhou Medical University,Xuzhou 221000,China;Department of Rehabilitation Medicine,Xuzhou City Hospital Affiliated to Xuzhou Medical University,Xuzhou 221000,China;Department of Respiratory and Critical Care Medicine,Xuzhou City Hospital Affiliated to Xuzhou Medical University,Xuzhou 221000,China;Coronary Care Unit,Xuzhou City Hospital Affiliated to Xuzhou Medical University,Xuzhou 221000,China)

机构地区：[1]徐州医科大学附属徐州市立医院心内科,江苏徐州221000 [2]徐州医科大学徐州临床学院,江苏徐州221000 [3]徐州医科大学附属徐州市立医院重症医学科,江苏徐州221000 [4]徐州医科大学附属徐州市立医院康复医学科,江苏徐州221000 [5]徐州医科大学附属徐州市立医院呼吸与危重症医学科,江苏徐州221000 [6]徐州医科大学附属徐州市立医院CCU,江苏徐州221000

出　　处：《长春中医药大学学报》2024年第11期1252-1255,共4页Journal of Changchun University of Chinese Medicine

基　　金：江苏省卫生健康委科研课题基金项目(Z2021073)。

摘　　要：目的本研究旨在评估体外膈肌起搏器(EDP)在慢性阻塞性肺疾病(COPD)急性加重期患者康复效果的影响。方法选取2021年4月—2024年1月徐州医科大学附属徐州市立医院收治的60例COPD急性加重期患者,随机分为观察组和对照组,各30例。观察组接受EDP治疗及常规治疗(抗感染、扩张支气管、镇咳、祛痰),而对照组仅接受常规治疗。研究主要评估了肺功能指标,包括第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、每分钟最大通气量(MVV);血气分析包括动脉氧分压(PaO_(2))和二氧化碳分压(PaCO_(2));症状评分包括6min步行试验、COPD评分、呼吸困难评分以及生活质量评分。结果治疗后,观察组在FEV1、FVC和MVV等肺功能指标上相比对照组有显著提高(P<0.05),PaO_(2)显著增加(P<0.05),PaCO_(2)显著减少(P<0.05)。此外,观察组的6 min步行距离、COPD评分和呼吸困难评分均比对照组有明显改善,生活质量的各项功能评分也显著提高(P<0.05)。结论EDP的使用显著提高COPD急性加重期患者的肺功能、缓解了症状并改善了生活质量,验证了其在COPD康复治疗的有效性和实用性。EDP不仅提高患者的运动康复能力,还显著改善患者的临床症状和生活质量。Objective To evaluate the effect of external diaphragm pacer(EDP)on the rehabilitation of patients with acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods 60 patients with acute exacerbation of COPD admitted to Xuzhou City Hospital Affiliated to Xuzhou Medical University from April 2021 to January 2024 were randomly divided into the observation group and the control group,with 30 patients in each group.The observation group received EDP treatment and conventional treatment(anti-infection,bronchodilator,cough control,and dispelling phlegm),while the control group only received conventional treatment.The study mainly evaluated lung function indicators[forced expiratory volume in the first second(FEV1),forced vital capacity(FVC),and maximum voluntary ventilation(MVV)per minute],blood gas indicators[partial arterial oxygen pressure(PaO_(2)),and partial carbon dioxide pressure(PaCO_(2))],and symptom scores[6-minute walk test,COPD scores,dyspnea,and quality of life].Results After treatment,compared with the control group,the observation group showed significant improvements in lung function indicators such as FEV1,FVC,and MVV(P<0.05),significant increase in PaO_(2)(P<0.05),and significant decrease in PaCO_(2)(P<0.05).In addition,compared with the control group,the 6-minute walking distance,COPD score,and dyspnea score of the observation group were significantly improved,and the functional scores of quality of life were also significantly improved(P<0.05).Conclusion The use of EDP significantly improves lung function,alleviates symptoms,and improves quality of life in patients with acute exacerbation of COPD,which validates its effectiveness and practicality in the rehabilitation treatment of COPD.EDP not only enhances patients'exercise rehabilitation ability,but also significantly improves clinical symptoms and quality of life.

关 键 词：体外膈肌起搏器 慢性阻塞性肺疾病 急性加重期呼吸康复训练 呼吸功能 生活质量 

分 类 号：R563.9[医药卫生—呼吸系统]