中国遗体器官捐献供肾体外低温机械灌注保存指南  

Guidelines for ex vivo hypothermic machine perfusion preservation of donor kidney from deceased organ donation in China

作　　者：中华医学会器官移植学分会 中国医师协会器官移植医师分会 中国医疗保健国际交流促进会肾脏移植学分会 丁晨光[2] 董建辉 高宝山[4] 吴江涛[5] 丁振山[6] 薛武 Branch of Organ Transplantation of Chinese Medical Association;Branch of Organ Transplantation Physician of Chinese Medical Doctor Association;Branch of Kidney Transplantation of China International Exchange and Promotive Association for Medical and Health Care;Xue Wujun;无(不详;The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区：[1]不详 [2]西安交通大学第一附属医院,西安710061 [3]广西医科大学第二附属医院 [4]吉林大学白求恩第一医院 [5]首都医科大学宣武医院 [6]中日友好医院

出　　处：《器官移植》2024年第6期837-845,共9页Organ Transplantation

基　　金：国家自然科学基金(82470782、82070768、82370755)。

摘　　要：为促进遗体器官捐献供肾体外低温机械灌注保存技术的规范应用,中华医学会器官移植学分会组织制定了《中国遗体器官捐献供肾体外低温机械灌注保存指南》。该指南整合了肾脏移植学和遗体器官捐献学领域的专家共识,依据现有的临床指南、系统评价、病例研究、专家共识等资料,并结合近年国内外遗体器官捐献供肾体外低温机械灌注保存技术的临床问题。在多次专家研讨和达成一致意见后,完成了该指南的撰写。该指南共包含11个临床问题,14条推荐意见,并按照2009版牛津大学循证医学中心的证据分级与推荐强度标准,对每个临床问题的推荐意见强度与证据级别进行了分级。该指南旨在为临床实践提供指导,提高我国遗体器官捐献供肾保存水平,减少器官弃用率,缓解器官短缺问题。In order to promote the standardized application of ex vivo hypothermic machine perfusionpreservation technology for donor kidney from deceased organ donation,Branch of Organ Transplantation of ChineseMedical Association organized the formulation of the"Guidelines for ex vivo hypothermic machine perfusion preservationof donor kidney from deceased organ donation in China".This guideline integrates expert consensus from thefields of kidney transplantation and deceased organ donation,based on existing clinical guidelines,systematic reviews,case studies,expert consensus,and other materials,and combined with clinical issues related to ex vivo hypothermicmachine perfusion preservation technology for kidneys from deceased organ donation in recent years both domesticallyand internationally.After multiple expert discussions and reaching a consensus,the guideline was completed.Theguideline contains 11 clinical questions and 14 recommendations,and the strength of recommendations and evidencelevels for each clinical question have been graded according to the 2009 Oxford Centre for Evidence-Based Medicinelevels of evidence and grades of recommendation.This guideline aims to provide guidance for clinical practice,improvethe level of donor kidney preservation from deceased organ donation in China,reduce the rate of organ discard,andalleviate the shortage of organs.

关 键 词：遗体器官捐献 肾脏移植 低温机械灌注 供肾保存 扩大标准供者 脑死亡器官捐献 心脏死亡器官捐献 移植物功能延迟恢复 

分 类 号：R617[医药卫生—外科学] R692[医药卫生—临床医学]