广西某三甲医院多重耐药菌监测结果分析  

Analysis of surveillance results for multidrug-resistant organisms in a tertiary hospital in Guangxi

作　　者：蔡秋伶 李阳[2] CAI Qiuling;LI Yang(Nanning Hospital of Traditional Chinese Medicine,Nanning 530001,Guangxi,China;Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China)

机构地区：[1]广西南宁市中医医院,广西南宁530001 [2]右江民族医学院,广西百色533000

出　　处：《右江民族医学院学报》2024年第5期741-745,共5页Journal of Youjiang Medical University for Nationalities

摘　　要：目的通过对多重耐药菌(multidrug-resistant organisms,MDROs)分布情况、感染特点等调查,以期能够针对性地制定多重耐药菌感染防控及干预措施,为阻断多重耐药菌传播提供理论基础。方法对某院2017—2021年多重耐药菌感染分布特点、感染的危险因素等进行描述统计和多因素Logistic回归分析。结果不同年龄、性别、住院时间之间MDROs感染发现率经过χ^(2)检验、χ^(2)趋势检验,差异有统计学意义(P<0.001),随着年龄的增大、住院时间的延长,MDROs感染发现率增大;Logistic回归分析显示:性别、年龄和住院天数均可影响MDROs感染的发生,男性比女性更易发生MDROs感染(OR=0.614,95%CI:0.569~0.664);年龄越大,越容易发生MDROs感染(OR=0.974,95%CI:0.972~0.976);住院时间越长,越容易发生MDROs感染(OR=0.967,95%CI:0.966~0.969)。经过描述性统计发现,MDROs感染发现率最高的科室是重症医学科,其次是呼吸内科和老年病科,下呼吸道、泌尿道和伤口是该院MDROs感染高发的部位。结论针对易感因素,应加强对男性、高龄、住院时间长、重症医学科、呼吸道感染患者的感染防控力度,通过采取合理的预防与控制措施,降低多重耐药菌的产生和传播,保障患者安全,提高医疗质量。Objective To investigate the distribution and infection characteristics of multidrug-resistant organisms(MDROs)in order to develop targeted prevention and intervention measures for MDROs infections,providing a theoretical basis for blocking the transmission of MDROs.Methods Descriptive statistics and multivariate Logistic regression analysis were conducted on the distribution characteristics and risk factors of MDROs infections in a tertiary hospital from 2017 to 2021.Results Theχ^(2) test andχ^(2) trend test revealed statistically significant differences in the incidence of MDROs infections among different age groups,genders,and lengths of hospital stay(P<0.001).With increasing age and length of hospital stay,the incidence of MDROs infections increased.Logistic regression analysis showed that gender,age,and length of hospital stay all influenced the occurrence of MDROs infections.Male patients were more susceptible to MDROs infections than female patients(OR=0.614,95%CI:0.569~0.664).Older age was associated with a higher incidence of MDROs infections(OR=0.974,95%CI:0.972~0.976).Longer lengths of hospital stay also increased the risk of MDROs infections(OR=0.967,95%CI:0.966~0.969).Descriptive statistics revealed that the department with the highest incidence of MDROs infections was the critical care medicine,followed by respiratory medicine and geriatrics.The lower respiratory tract,urinary tract,and wounds were the most common sites of MDROs infections in the hospital.Conclusion In response to predisposing factors,enhanced infection prevention and control measures should be implemented for patients who are male,elderly,have prolonged hospital stays,are in intensive care units,or have respiratory tract infections.By adopting reasonable prevention and control strategies,the emergence and transmission of MDROs can be reduced,thereby ensuring patient safety and improving medical quality.

关 键 词：多重耐药菌 危险因素 交叉感染 

分 类 号：R639[医药卫生—外科学]