家蚕泛基因组及多组学数据库SilkMeta  

The Silkworm Pan-genomic and Multi-omic Database SilkMeta

作　　者：陆昆鹏[1] 潘奕霏 韩民锦[1] 童晓玲[1] 代方银[1] LU Kunpeng;PAN Yifei;HAN Minjin;TONG Xiaoling;DAI Fangyin(State Key Laboratory of Resource Insects/Key Laboratory of Sericultural Biology and Genetic Breeding,Ministry of Agriculture and Rural Affairs/College of Sericulture,Testile and Biomass Sciences,Southwvest University,Chongqing 400716,China)

机构地区：[1]资源昆虫高效养殖与利用全国重点实验室/农业农村部蚕桑生物学与遗传育种重点实验室/西南大学蚕桑纺织与生物质科学学院,重庆400716

出　　处：《蚕学通讯》2024年第3期19-23,共5页Newsletter of Sericultural Science

基　　金：国家自然科学基金项目(32330102,U20A2058,32202746);财政部和农业农村部:国家现代农业产业技术体系建设专项(CARS-18-ZJ0102,CARS-18-ZJ0103);重庆市自然科学基金创新群体项目(cstc2021jcyj-cxtt0005)。

摘　　要：家蚕是重要的经济昆虫,也是研究鳞翅目的模式物种。本团队2022年公布的家蚕泛基因组数据集是育种和规模化高效解析家蚕基因型-表型关系的重要组学信息资源。本文介绍了以该数据集为主体,整合其他多组学数据构建而成的一个家蚕泛基因组和多组学数据库——SilkMeta(http://silkmeta.org.cn)。该数据库主要包括546个高质量基因组、1 082个样本的超过5 000万个基因组变异(SNP、InDel、SV)、1 168个转录组、非编码RNA、全长转录本、人工选择信号、遗传连锁图谱、群体结构、表型及常用生物信息分析工具等,为开展家蚕功能基因组学研究提供了一个可交互式访问、用户友好的组学数据共享分析平台。该平台在家蚕种质资源遗传评价、性状基因解析、精准分子改良和基因组选择育种及昆虫发育、适应性进化等研究方面将发挥重要的支撑作用。he silkworm Bombya mori is an important economic insect and a model species for studying lepidopteran insects.The silkworm pan-genome dataset released by our group in 2022 is an important resource for breeding and efficiently deciphering the genotype-phenotype relationship of silkworms.Here,we introduce SilkMeta(http://silkmeta.org.cn),a silkworm pan-genomic and multi-omics database constructed by integrating other multi-omics data with pan-genomic dataset as the main part.SilkMeta includes 546 high-quality genomes,over 50 million genomic variations(SNPs,InDel,SV)from 1082 samples,1168 transcriptomes,non-coding RNAs,full-length transcripts,artificial selection signals,genetic linkage maps,population structure,phenotypes,and some useful bioinformatics analysis tools.It is an interactive and user-friendly platform for sharing and analyzing omics data,and will facilitate functional genomics research in silkworms.This platform plays an important role in supporting studies for the genetic evaluation,phenotype-associated gene uncovering,precise molecular improvement,and genome selection breeding of silkworms,as well as the development and adaptive evolution of insects.

关 键 词：家蚕 泛基因组 多组学 数据库 

分 类 号：S881.26[农业科学—特种经济动物饲养]