Performance analysis of markers for prostate cell typing in single-cell data  

作　　者：Yanting Shen Xiawei Fei Junyan Xu Rui Yang Qinyu Ge Zhong Wang 

机构地区：[1]Department of Urology,Shanghai Ninth People's Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China [2]Department of Urology and Andrology,Gongli Hospital,The Second Military Medical University,Shanghai 200135,China [3]State Key Laboratory of Bioelectronics,School of Biological Science and Medical Engineering,Southeast University,Nanjing,Jiangsu 210096,China [4]Wuxi Maternal and Child Health Hospital,Wuxi School of Medicine,Jiangnan University,Jiangsu 214002,China [5]Department of Urology,Qingpu Branch of Zhongshan Hospital Affiliated toFudan University,Shanghai 201799,China [6]University of Shanghai for Science and Technology,Shanghai 200093,China

出　　处：《Genes & Diseases》2024年第6期52-55,共4页基因与疾病（英文）

基　　金：supported by the National Natural Science Foundation of China,China (No.62101319,82170788);the Medical Discipline Construction Project of the Health System of Pudong New Area (China) (No.PYWgf2021-06).

摘　　要：Cell typing is an important step in the single-cell RNA sequencing(scRNA-seq)analysis.Although some cell marker databases and cell typing tools have been proposed,limited roles are in prostate cell typing.Through literature review,we found prostate cell typing relied much on researchers'knowledge and experience,thus different markers were used to label the same cell type,leading to the divergences between studies,emphasizing the importance of a sound epistemological foundation for prostate cell typing in single-cell data.

关 键 词：ANALYSIS ANALYSIS TYPING 

分 类 号：R697.3[医药卫生—泌尿科学]