Ageing-related bone and immunity changes:insights into the complex interplay between the skeleton and the immune system  

作　　者：Bobin Mi Yuan Xiong Samuel Knoedler Michael Alfertshofer Adriana C.Panayi Haixing Wang Sien Lin Gang Li Guohui Liu 

机构地区：[1]Department of Orthopedics,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,1277 Jiefang Avenue,Wuhan 430022,China [2]Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration,Wuhan 430022,China [3]Division of Plastic Surgery,Department of Surgery,Brigham and Women’s Hospital,Harvard Medical School,Boston,MA,USA [4]Institute of Regenerative Biology and Medicine,Helmholtz Zentrum München,Munich,Germany [5]Division of Hand,Plastic and Aesthetic Surgery,Ludwig-Maximilian University Munich,Munich,Germany [6]Department of Hand-,Plastic and Reconstructive Surgery,Microsurgery,Burn Trauma Center,BG Trauma Center Ludwigshafen,University of Heidelberg,Ludwigshafen,Germany [7]Department of Orthopaedics&Traumatology,Stem Cells and Regenerative Medicine Laboratory,Li Ka Shing Institute of Health Sciences,The Chinese University of Hong Kong,Prince of Wales Hospital,Shatin,Hong Kong,SAR 999077,P.R.China

出　　处：《Bone Research》2024年第3期502-516,共15页骨研究（英文版）

基　　金：supported by the National Key R&D Program of China (2021YFA1101500);Wuhan Science and Technology Bureau (2022020801020464);partially supported by University Grants Committee,Research Grants Council of the Hong Kong Special Administrative Region,China (14113723,N_CUHK472/22,T13-402/17-N and AoE/M-402/20);Direct Grant of CUHK (2022.042)。

摘　　要：Ageing as a natural irreversible process inherently results in the functional deterioration of numerous organ systems and tissues,including the skeletal and immune systems.Recent studies have elucidated the intricate bidirectional interactions between these two systems.

关 键 词：SKELETON INSIGHT IRREVERSIBLE 

分 类 号：R592[医药卫生—老年医学]