孕晚期妇女B族链球菌实验室筛查情况及相关药敏试验结果分析  

Analysis of laboratory screening for group B Streptococcus and related drug sensitivity test results in women in late pregnancy

作　　者：雷雪明 田欣 LEI Xue-ming;TIAN Xin(Department of Clinical Laboratory,Weihai Maternal and Child Health Care Hospital,Weihai 264200,China)

机构地区：[1]威海市妇幼保健院检验科,264200

出　　处：《中国现代药物应用》2024年第20期67-69,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨孕晚期妇女B族链球菌(GBS)实验室筛查情况及相关药敏试验结果。方法选取3983例自愿接受产前GBS筛查的孕晚期妇女为研究对象,取阴拭子进行细菌培养筛查GBS感染情况,并对相应的菌株做药敏试验分析。结果共筛查孕妇3983例,检测出231株GBS,阳性率为5.80%。GBS对于氨苄西林、替加环素、头孢吡肟、头孢曲松、利奈唑胺、青霉素、万古霉素、头孢噻肟的敏感率达99.00%以上,对左氧氟沙星、红霉素、克林霉素、莫西沙星的耐药率分别53.68%、72.29%、63.20%、54.11%。结论GBS对β内酰胺类药物高度敏感,对喹诺酮和大环内酯类药物高度耐药,仍需加强GBS的耐药检测。Objective To investigate the laboratory screening for group B Streptococcus(GBS)and related drug sensitivity test results in women in late pregnancy.Methods 3983 pregnant women who voluntarily accept prenatal GBS screening were taken as research subjects,vaginal swabs were used for bacterial culture to screen GBS infection and the corresponding strains were analyzed by drug sensitivity test.Results A total of 3983 pregnant women were screened,231 strains of GBS were detected,the positive rate was 5.80%.The sensitivity rate of GBS to ampicillin,tigecycline,cefepime,ceftriaxone,linezolid,penicillin,vancomycin,and cefotaxime were all over 99.00%.The resistance rates to levofloxacin,erythromycin,clindamycin,and moxifloxacin were 53.68%,72.29%,63.20%,and 54.11%,respectively.Conclusion GBS is highly sensitive toβ-lactam drugs and highly resistant to quinolones and macrolides,and the resistance test for GBS still need to be strengthened.

关 键 词：孕晚期 B族链球菌 药敏试验 

分 类 号：R446.5[医药卫生—诊断学] R714.2[医药卫生—临床医学]