针药并用治疗输卵管阻塞性不孕症的Meta分析  

Meta-analysis of the treatment of tubal obstructive infertility by combination of acupuncture and medicine

作　　者：周星 张同梅 王丹 徐夏菲 梁凤娟 ZHOU Xing;ZHANG Tong-mei;WANG Dan(Zaozhuang Hospital of Traditional Chinese Medicine,Zaozhuang 277000,China)

机构地区：[1]枣庄市中医医院,277000

出　　处：《中国现代药物应用》2024年第20期94-98,共5页Chinese Journal of Modern Drug Application

基　　金：2021年度山东省中医药科技项目(项目编号:2021Q046)。

摘　　要：目的评价针药并用治疗输卵管阻塞性不孕症的临床疗效。方法通过检索SinoMed、中国知网、万方和维普,收集2018年1月~2022年12月发表过的有关针药并用治疗输卵管阻塞性不孕症的临床研究文献,采用Revman5.3软件对纳入文献进行Meta分析。结果纳入26篇文献,Meta分析结果示:试验组的总有效率高于对照组,差异具有统计学意义[相对危险度(RR)=1.28,95%可信区间(CI)=(1.22,1.33),P<0.00001];试验组的妊娠率高于对照组,差异具有统计学意义[RR=1.71,95%CI=(1.42,2.06),P<0.00001];试验组输卵管通畅率高于对照组[RR=1.54,95%CI=(1.42,1.68),P<0.00001]。结论相对以往常规非针药结合疗法,针药并用可提高输卵管阻塞性不孕症的治疗效果、妊娠率和输卵管通畅率,也可以避免因手术治疗所致的粘连发生,因其不良反应较少,临床效果和安全性较高。Objective To evaluate the clinical effect of combination of acupuncture and medicine in the treatment of tubal obstructive infertility.Methods By searching SinoMed,CNKI,Wanfang,and VIP,clinical research literatures on the combination of acupuncture and medicine in the treatment of tubal obstructive infertility published from January 2018 to December 2022 were collected,and Meta-analysis was performed on the included literatures using Revman5.3 software.Results 26 papers were included,and Meta-analysis showed that the total effective rate of the test group was higher than that of the control group,and the difference was statistically significant[relative risk(RR)=1.28,95%confidence interval(CI)=(1.22,1.33);P<0.00001].The pregnancy rate in the test group was higher than that in the control group,and the difference was statistically significant[RR=1.71;95%CI=(1.42,2.06);P<0.00001].The rate of tubal patency in the test group was higher than that in the control group[RR=1.54;95%CI=(1.42,1.68);P<0.00001].Conclusion Compared with the previous conventional non-acupuncture-medicine combination therapy,the combination of acupuncture and medicine can improve the therapeutic effect,pregnancy rate and tubal patency rate of tubal obstructive infertility,and can also avoid the occurrence of adhesion due to surgical treatment,with fewer adverse reactions and higher clinical effectiveness and safety.

关 键 词：针药并用 输卵管阻塞性不孕症 META分析 

分 类 号：R711.6[医药卫生—妇产科学] G353.1[医药卫生—临床医学]