孕早期维生素D水平检测与妊娠期糖尿病关系分析  

Analysis of the Relationship Between the Level of Vitamin D in Early Pregnancy And Diabetes in Pregnancy

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作  者:兰旭兰 LAN Xulan(Department of Gynecology and Obstetrics,Community Health Service Center of Xiamen Huli District Jiangtou Street,Xiamen 361000,China)

机构地区:[1]厦门市湖里区江头街道社区卫生服务中心妇产科,厦门361000

出  处:《中国医药指南》2024年第31期86-88,共3页Guide of China Medicine

摘  要:目的探讨孕早期维生素D水平检测与妊娠期糖尿病关系分析。方法选择2022年10月至2023年10月厦门市湖里区江头街道社区卫生服务中心妇产科进行产前建卡,予检测孕早期维生素D水平的300例妊娠孕妇为探究对象,按照糖耐量试验检测结果分为妊娠期糖尿病组(200例)、非妊娠期糖尿病组(100例),采取化学免疫发光法检测上述两组患者25-羟基维生素D[25(OH)D]水平,对比孕早期孕妇25(OH)D水平、血糖水平及妊娠期糖尿病发生的风险性。结果妊娠期糖尿病组空腹血糖、甘油三酯、口服葡萄糖耐量试验(OGTT)各时间段血糖水平较非妊娠期糖尿病组高(P<0.05),组间低密度脂蛋白胆固醇、空腹胰岛素对比无统计学意义(P>0.05);检测后,妊娠期糖尿病25(OH)D缺乏率较非妊娠期糖尿病组高(P<0.05)。结论孕妇机体缺乏维生素D时会诱导后期出现妊娠期糖尿病,需加强孕期监测并及时补充维生素,有助于预防后期妊娠期糖尿病的出现。Objective To investigate the relationship between the level of vitamin D in early pregnancy and diabetes in pregnancy.Methods From October 2022 to October 2023,A total of 300 pregnant women were selected from the obstetrics and gynecology department of the Community Health Service Center in Jiangtou Street,Huli District,Xiamen City for prenatal card building,and the vitamin D level in the early pregnancy was measured.According to the glucose tolerance test results,they were divided into the pregnant diabetes group(200 cases)and the non pregnant diabetes group(100 cases).The 25 hydroxyvitamin D[25(OH)D]level of the above two groups of patients was measured by chemical immunoluminescence method,and the 25(OH)D level,blood glucose level and the risk of diabetes in the early pregnancy were compared.Results The levels of fasting blood glucose,triglyceride and oral glucose tolerance test(OGTT)in gestational diabetes group were higher than those in non-gestational diabetes group(P<0.05),there was no significant difference in low density lipoprotein cholesterol and fasting insulin between groups(P>0.05).After detection,the 25(OH)D deficiency rate of gestational diabetes mellitus was higher than that of nongestational diabetes mellitus group(P<0.05).Conclusions The lack of vitamin D in pregnant women will induce diabetes in late pregnancy.It is necessary to strengthen the monitoring during pregnancy and supplement vitamin in time,which is helpful to prevent the occurrence of diabetes in late pregnancy.

关 键 词:孕早期 维生素D水平 妊娠期糖尿病 相关性 血糖 血脂 

分 类 号:R714.256[医药卫生—妇产科学]

 

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