肠闭锁术后患儿肠功能障碍发生的多因素分析——基于某地的调查报告  

Multivariate Analysis of Intestinal Dysfunction in Children with Postoperative Intestinal Atresia:Based on A Survey Report Somewhere

作　　者：明振奇 王力 MING Zhen-qi;WANG Li(Department of Neonatology,Tengzhou Maternal and Child Health Hospital,Zaozhuang,Shandong 277500)

机构地区：[1]山东省滕州市妇幼保健院新生儿科,山东枣庄277500

出　　处：《中国肛肠病杂志》2024年第9期15-18,共4页Chinese Journal of Coloproctology

摘　　要：目的:探讨与分析肠闭锁术后患儿肠功能障碍的发生因素,以预防肠功能障碍的发生。方法:选取2018年8月至2023年5月,滕州地区多家三级医院诊治的82例先天性肠闭锁新生儿,将其中12例发生肠功能障碍的患儿列为障碍组,70例肠功能正常患儿列为正常组。统计分析所有患儿的临床资料,记录肠功能障碍发生情况并进行多因素分析。结果:82例患儿中,术后第1次平均通便时间为(3.22±0.21)d。2组在性别、日龄、出生体重方面比较,差异无统计学意义(P>0.05),在早产、体重、闭锁位置、病理分型、肺部感染和吻合口漏方面,2组比较差异有统计学意义(P<0.05)。经Logistic回归分析显示早产、闭锁位置、体重、病理分型、肺部感染和吻合口漏为导致肠闭锁术后患儿肠功能障碍发生的危险因素(P<0.05)。Pearson分析显示早产、体重、闭锁位置、病理分型、肺部感染和吻合口漏与肠闭锁术后患儿第1次通便时间存在正相关性(P<0.05)。结论:肠闭锁术后患儿肠功能障碍发生率较高,体重、早产、闭锁位置、病理分型、肺部感染和吻合口漏为导致肠闭锁术后肠功能障碍发生的危险因素。Objective To explore and analyze the factors of intestinal dysfunction in children after intestinal atresia,so as to prevent the occurrence of intestinal dysfunction.Methods From August 2018 to May 2023,total 82 newborns with congenital intestinal atresia were selected from several tertiary hospitals in Tengzhou area,among which 12 children with intestinal dysfunction were classified as the disorder group,and 70 children with normal intestinal function were classified as the normal group.The clinical data of all the children were statistically analyzed,and the incidence of intestinal dysfunction was recorded and multivariate analysis was performed.Results In 82 cases,the mean time of the first postoperative defecation was(3.22±0.21)d.There was no significant difference between the two groups in terms of gender,age and birth weight(P>0.05),but there were significant differences between the two groups in terms of premature birth,body weight,atresia location,pathological classification,pulmonary infection and anastomotic leakage(P<0.05).The results of Logistic regression analysis showed that preterm birth,atresia location,body weight,pathological classification,pulmonary infection and anastomotic leakage were the risk factors for intestinal dysfunction in postoperative children with intestinal atresia(P<0.05).Pearson analysis showed that preterm birth,body weight,atresia location,pathologic classification,pulmonary infection and anastomotic leakage were positively correlated with the time of first bowel movement in postoperative children with intestinal atresia(P<0.05).Conclusion The incidence of intestinal dysfunction is higher in postoperative children with intestinal atresia.Weight,premature delivery,location of atresia,pathological classification,pulmonary infection and anastomotic leakage are the risk factors for postoperative intestinal dysfunction of intestinal atresia.

关 键 词：先天性肠闭锁 肠功能障碍 影响因素 

分 类 号：R726.5[医药卫生—儿科]