整合诊疗功能的外科缝合线的研究进展  

Research Progress of Surgical Sutures with Integrated Diagnostic and Therapeutic Functions

作　　者：王晓贺 徐琳[2] 付丽[1] WANG Xiao-He;XU Lin;FU Li(Department of Implantology,Hospital of Stomatology,Jilin University,Changchun 130021,China;State Key Laboratory of Integrated Optoelectronics,College of Electronic Science and Engineering,Jilin University,Changchun 130012,China)

机构地区：[1]吉林大学口腔医学院,长春130021 [2]吉林大学电子科学与工程学院,集成光电子学国家重点实验室,长春130012

出　　处：《应用化学》2024年第10期1399-1408,共10页Chinese Journal of Applied Chemistry

摘　　要：慢性难愈性伤口是影响全球数百万人健康的问题之一,及时地评估伤口状况并实施有效的治疗对于伤口愈合管理至关重要,然而这仍是一项临床难题。外科缝合线在伤口组织的闭合和愈合方面发挥着重要作用。近年来,通过物理及化学方法修饰缝合线,赋予其监测和促愈合功能已成为研究热点。目前,相关研究在缝合线的材料、结构设计和功能化以及智能化修饰方面均取得了可观的进展。文章阐述了缝合线的分类和功能,介绍了构建功能性诊疗缝合线的策略及研究进展,并探讨功能性缝合线面对的挑战和未来前景,旨在为智能诊疗缝合线的设计和研究方向提供思路和参考。Chronic hard-to-heal wounds are one of the health problems affecting millions of people worldwide.Assessing the wound condition promptly and implementing effective treatments are essential for wound healing management,yet this remains a clinical challenge.Surgical suture plays an important role in the closure and healing of wound tissue.In recent years,it has become a research hotspot to modify sutures using physical and chemical methods,endowing them with monitoring and pro-healing functions.The current relevant research has made considerable progress in the materials,structural design and functionalization of sutures and intelligent modifications.This paper describes the classification and function of sutures,introduces the strategies for constructing functional diagnostic sutures and their research progress,and discusses the challenges and prospects faced by functional sutures.It aims to provide ideas and references for the design and research direction of intelligent diagnostic sutures.

关 键 词：缝合线 伤口愈合 伤口监测 感染 组织修复 

分 类 号：O631[理学—高分子化学]