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作 者:Zenglong Yan Shuyuan Zhang Ling Ren Xizhuang Bai Ke Yang Xiang Wei
机构地区:[1]Dalian Medical University,Dalian,116046,China [2]Institute of Metal Research,Chinese Academy of Sciences,Shenyang,110016,China [3]Liaoning People’s Hospital,Shenyang,110013,China [4]Suzhou Silvan Medical Co Ltd,Suzhou,215000,China
出 处:《Acta Metallurgica Sinica(English Letters)》2024年第10期1767-1776,共10页金属学报(英文版)
基 金:financially supported by the Natural Science Foundation of Liaoning Province(No.2022-MS-079).
摘 要:This study used an anodic etching(AE)method to construct a hierarchical rough surface on the surface of the Cu-bearing antibacterial titanium alloy,Ti-xCu(x=3,5,7 wt%),a three-dimensional structure with nested micro-/submicro-pores and internal cavities,which is conducive to the adhesion and growth of bone cells.After AE treatment,with increase of the Cu content in the alloy,the surface of Ti-Cu alloy became sharper,with more fine micropores and internal cavities,thus increasing the surface area.The results indicated that the AE/Ti-Cu alloy exhibited good antibacterial properties and had the effect of inhibiting bacterial biofilm formation.AE treatment could increase the Cu ions release of Ti-Cu alloy in saline,and the higher the Cu content in the alloy,the more Cu ions release,resulting in stronger antibacterial performance of the alloy.AE/Ti-Cu alloy showed excellent biocompatibility,similar to the pure Ti.Therefore,anodic etching is a safe and effective surface treatment method for Ti-Cu alloy,with good clinical application prospects.
关 键 词:Ti-Cu alloy Anodic etching Rough surface Antibacterial performance BIOCOMPATIBILITY
分 类 号:TG146.23[一般工业技术—材料科学与工程]
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