高性能生物医用聚乳酸/聚己内酯共混物的微型注塑制备及后处理  

Preparation of High-Performance Polylactic Acid/Polycaprolactone Blend Biomedical Micropart via Microinjection Molding and Post Treatment

作　　者：冯硕 谭佳宇 陈英红[1] 陈美琼 周新闻 陈宁[1] Shuo Feng;Jiayu Tan;Yinghong Chen;Meiqiong Chen;Xinwen Zhou;Ning Chen(State Key Laboratory of Polymer Materials Engineering,Polymer Research Institute of Sichuan University,Chengdu 610065,China)

机构地区：[1]高分子材料工程国家重点实验室四川大学高分子研究所,四川成都610065

出　　处：《高分子材料科学与工程》2024年第9期118-127,共10页Polymer Materials Science & Engineering

基　　金：国家重点研发计划(2022YFC3901805);国家自然科学基金资助项目(U21A2091&51773121);四川省国际科技创新合作项目(2024YFHZ0232);四川大学工科共性学科特色方向项目(2020SCUNG203);四川省青年科技创新团队项目(22CXTD0019)。

摘　　要：在熔融共混制备聚乳酸(PLA)/聚己内酯(PCL)共混物的基础上,采用微型注塑先进加工技术结合退火处理的方法,成功制备了高性能的PLA/PCL共混物生物医用微型制品。扫描电子显微镜和小角X射线散射结果表明,微型注塑过程中产生的强大剪切应力场促进了共混物分散相PCL纤维在制品中的原位形成,同时形成了以PCL为纤维晶、PLA为片晶的杂化shish-kebab结构。随后的退火处理进一步完善了体系中形成的PLA片晶,并促成了与PCL纤维之间的互锁结构形成。力学性能测试结果表明,经过退火处理的微型制品表现出更好的韧性,其最大断裂伸长率达到了68.1%,是纯PLA微型注塑制品的7倍。同时,退火处理样品的弹性模量高于纯PLA制品。上述结果表明,微型注塑结合退火处理所得到的PLA/PCL共混物微型制品兼具良好的强度和韧性,为制备高性能可降解的PLA基生物医用微型器件提供了新的方法,具有广阔的应用前景。On the basis of preparing polylactic acid(PLA)/polycaprolactone(PCL)blend through melt compounding,the combination of microinjection molding technology with annealing treatment strategy was adopted to successfully fabricate the high performance biomedical micropart.Scanning electron microscopy(SEM)and small-angle X-ray scattering(SAXS)measurements show that the robust shear stress field generated during microinjection molding facilitates the in-situ formation of PCL fibers within the micropart products,resulting in a hybrid shish-kebab structure with PCL fiber as core shish and PLA lamellar crystal as kebab.The subsequent annealing treatment further refines the PLA kebab lamellar crystals formation and facilitates the formation of interlocking structures between PCL fibers.The tensile tests indicate that the annealed products exhibit the enhanced toughness,with the maximum elongation at break reaching 68.1%,which is 7 times higher than that of pure PLA micro injection molded products.Additionally,the annealed samples show the higher elastic modulus than the pure PLA ones.The above results clearly show that the PLA/PCL blend microparts prepared through combining microinjection molding with annealing treatment possess the excellent strength and toughness,offering a novel approach for the fabrication of high-performance biodegradable PLA-based biomedical microparts with promising application prospect.

关 键 词：微型注塑 聚乳酸 原位成纤 退火处理 力学性能 

分 类 号：TQ323.4[化学工程—合成树脂塑料工业]