绝经后女性膝骨性关节炎患者胫骨平台内翻与骨质疏松的相关性分析  

Correlation analysis between tibial plateau varus and osteoporosis in postmenopausal women with knee osteoarthritis

作　　者：赵君禄[1] 刘斋[1] 高艺铭 李敬玉[1] 任庆云[1] ZHAO Junlu;LIU Zhai;GAO Yiming;LI Jingyu;REN Qingyun(Department of Radiology,the First Hospital of Hebei Medical University,Shijiazhuang 050031,China)

机构地区：[1]河北医科大学第一医院放射科,河北石家庄050031

出　　处：《实用放射学杂志》2024年第10期1674-1677,共4页Journal of Practical Radiology

基　　金：河北省财政厅基金项目(LS201804)。

摘　　要：目的探讨绝经后女性膝骨性关节炎(KOA)患者胫骨平台内翻与骨质疏松(OP)的相关性。方法回顾性分析接受膝关节单髁置换术的绝经后女性KOA患者194例。收集并分析与胫骨平台内翻[胫骨平台内侧角(MTPA)<85°]相关的危险因素,包括年龄、体质量指数(BMI)、凯格伦-劳伦斯(K-L)分级、髋膝踝角(HKAA)、股骨远端外侧角(LDFA)及骨密度(BMD)。采用多元回归分析这些因素与胫骨平台内翻的关系。采用Pearson相关分析MTPA与BMD的相关性。结果采用多元线性回归分析结果显示,BMD(β=0.381,P<0.001)及HKAA(β=0.460,P<0.001)是胫骨平台内翻的独立危险因素。LDFA、年龄、BMI、K-L分级与胫骨平台内翻无明显相关性。Pearson相关分析显示BMD与胫骨平台内翻显著相关(r=0.817,P<0.001),对于膝关节内翻(HKAA<175°)的患者,BMD与胫骨平台内翻显著相关(r=0.781,P<0.001)。对于下肢力线正常(HKAA≥175°)的患者,BMD与胫骨平台内翻之间无显著相关(r=-0.035,P=0.063)。结论OP及膝关节内翻是绝经后女性KOA患者膝关节胫骨平台内翻的主要危险因素。Objective To investigate the correlation between tibial plateau varus and osteoporosis(OP)in postmenopausal women with knee osteoarthritis(KOA).Methods A retrospective analysis was conducted on 194 postmenopausal women with KOA who underwent unicompartmental knee arthroplasty.Various risk factors associated with tibial plateau varus[medial tibial plateau angle(MTPA)<85°],including age,body mass index(BMI),Kellgren-Lawrence(K-L)grade,hip-knee-ankle angle(HKAA),lateral distal femur angle(LDFA),bone mineral density(BMD)were collected and analyzed.Multiple regression was employed to analyze the relationship of these factors with tibial plateau varus.Pearson’s correlation coefficient was used to assess the association between MTPA and BMD.Results Multiple linear regression analysis revealed that BMD(β=0.381,P<0.001)and HKAA(β=0.460,P<0.001)were independent risk factors for tibial plateau varus.LDFA,age,BMI,K-L grade were not significantly associated with tibial plateau varus.A statistically significant association between BMD and tibial plateau varus was noted(r=0.817,P<0.001).Further data stratification showed a significant association between BMD and tibial plateau varus in patients with knee varus(HKAA<175°)(r=0.781,P<0.001).There was no statistical significance association between BMD and tibial plateau varus in patients with normal lower extremity alignment(HKAA≥175°)(r=-0.035,P=0.063).Conclusion OP and knee varus emerge as the primary risk factors for tibial plateau varus in the knee in postmenopausal women with KOA.

关 键 词：骨质疏松 膝骨性关节炎 单髁置换术 胫骨平台内翻 

分 类 号：R681[医药卫生—骨科学] R684.3[医药卫生—外科学] R687.3[医药卫生—临床医学]