舌下含服硝酸甘油对膝骨性关节炎患者膝关节周围动脉CT成像的影响  

Effect of sublingual nitroglycerin on CT imaging of peripheral arteries of knee joint in patients with knee osteoarthritis

作　　者：宋芹霞[1] 王祥发 陈峰 SONG Qinxia;WANG Xiangfa;CHEN Feng(Department of Medical Imaging,Anqing Municipal Hospital,Anqing,Anhui Province 246003,China;Department of Internal Medicine,Anqing Second People’s Hospital,Anqing,Anhui Province 246004,China)

机构地区：[1]安庆市立医院医学影像科,安徽安庆246003 [2]安庆市第二人民医院内科,安徽安庆246004

出　　处：《实用放射学杂志》2024年第10期1678-1682,共5页Journal of Practical Radiology

基　　金：安庆市立医院院级科研基金项目(2022aqykj22)。

摘　　要：目的探讨舌下含服硝酸甘油(NTG)片对膝骨性关节炎(KOA)患者膝关节周围CT血管成像(CTA)质量的影响。方法将100例KOA患者纳入研究,行下肢CTA之前随机分为2组(服药组40例和对照组60例)。比较CTA图像的对比噪声比(CNR),并利用Likert 5分法评价和比较整体图像质量和血管分级。测量腘动脉(PA)、胫前动脉(ATA)、胫后动脉(PTA)、腓动脉(PeA)、膝降动脉(DGA)、外侧膝上动脉(LSGA)、内侧膝上动脉(MSGA)、膝中动脉(MGA)、内侧膝下动脉(MIGA)、外侧膝下动脉(LIGA)、胫前返动脉(ATRA)的管径,并统计2组膝关节周围动脉可见数量,进行组间比较。结果服药组膝关节周围动脉的CNR和整体CTA图像质量显著高于对照组(P<0.05)。PA及其分支的管腔直径在服药组显著增大(P<0.05)。与对照组相比,服药组显示血管数量显著增加(P<0.05)。结论舌下含服NTG应用于膝关节周围动脉CTA可增加膝关节周围动脉管径,提高CTA图像质量和可见动脉数量。Objective To investigate the effect of sublingual nitroglycerin(NTG)tablets on the quality of computed tomography angiography(CTA)around the knee joint in patients with knee osteoarthritis(KOA).Methods A total of 100 patients with KOA were included in the study and randomly divided into two groups before lower limb CTA(40 cases in the medication group and 60 cases in the control group).The contrast-to-noise ratio(CNR)of CTA images were compared,and the overall image quality and vascular grading were evaluated and compared using the Likert 5-point method.The diameter of the popliteal artery(PA),anterior tibial artery(ATA),posterior tibial artery(PTA),peroneal artery(PeA),descending genicular artery(DGA),lateral superior genicular artery(LSGA),medial superior genicular artery(MSGA),middle genicular artery(MGA),medial inferior genicular artery(MIGA),lateral inferior genicular artery(LIGA),and anterior tibial recurrent artery(ATRA)were measured.Furthermore,the number of visible arteries around the knee joint between the two groups were calculated and compared.Results The CNR and overall CTA image quality of arteries around the knee joint in the medication group were significantly higher than those in the control group(P<0.05).Moreover,the lumen diameter of the PA and its branches significantly increased in the medication group(P<0.05).In comparison to control group,the number of visible vessels significantly increased in the medication group(P<0.05).Conclusion Sublingual administration of NTG during CTA examination can effectively increase arterial diameter around the knee joint,resulting in improved image quality as well as an increased number of visible arteries.

关 键 词：硝酸甘油 双源CT CT血管成像 膝骨性关节炎 

分 类 号：R814.42[医药卫生—影像医学与核医学] R684.3[医药卫生—放射医学]