Impact of single chamber and dual chamber permanent pacemaker implantation on left ventricular function:An observational study  

作　　者：Merajul Haque Monika Bhandari Akshyaya Pradhan Pravesh Vishwakarma Abhishek Singh Ayush Shukla Akhil Sharma Gaurav Chaudhary Rishi Sethi Sharad Chandra Arvind Jaiswal Sudhanshu Kumar Dwivedi 

机构地区：[1]Department of Cardiology,BRD Medical College,Gorakhpur 273013,Uttar Pradesh,India [2]Department of Cardiology,King George’s Medical University,Lucknow 226003,Uttar Pradesh,India

出　　处：《World Journal of Cardiology》2024年第11期644-650,共7页世界心脏病学杂志（英文）

摘　　要：BACKGROUND Permanent pacemaker implantation has the potential to impact left ventricular(LV)function and hence quality of life(QoL)in the long term.AIM To assess the effect of single-and dual-chamber pacing on LV function and QoL.METHODS This study included 56 patients who underwent permanent pacing:Dual pacing,dual sensing,dual responsive and rate responsive(DDDR)for the initial 3 months,ventricular sensing,inhibited response and rate responsive(VVIR)for the next 3 months,and DDDR mode for the last 3 months.Throughout the study period,various echocardiographic parameters,functional status,and QoL were measured to assess the impact of pacing on LV function compared with baseline and at every 3 months interval.RESULTS A significant change appeared in cardiac function after VVIR pacing which was in diastolic properties of LV as shown by increase in isovolumic relaxation time from(85.28±9.54 ms)to(89.53±9.65 ms).At the 3-,6-,and 9-month follow-up,reduction in LV ejection fraction was observed to be 62.71±4.66%,61.07±4.41%,and 58.48±3.89%,respectively.An increase in the QoL scores was noted at every follow-up visit.CONCLUSION An apparent depressant effect on LV function due to right ventricular pacing,with a higher incidence of adverse outcomes in the VVIR mode.In addition,an upsurge in QoL scores for the study population was noted,which indicates improvement in the QoL of patients post-pacing,irrespective of the mode.Generally,the DDDR mode is a highly preferable pacing mode.

关 键 词：Artificial pacemaker ECHOCARDIOGRAPHY Left ventricular function Quality of life 

分 类 号：R54[医药卫生—心血管疾病]