Blue rubber blister nevus syndrome: A case report  

作　　者：Wen-Jing Wang Pei-Li Chen Huan-Zhang Shao 

机构地区：[1]Department of Critical Care Medicine,Henan Provincial People's Hospital,People's Hospital of Zhengzhou University,Zhengzhou 450003,Henan Province,China [2]Department of Critical Care Medicine,Henan Provincial People's Hospital,People's Hospital of Henan University,Zhengzhou 450003,Henan Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第11期3584-3589,共6页世界胃肠外科杂志（英文）

摘　　要：BACKGROUND Blue rubber blister nevus syndrome(BRBNS)is a congenital,rare disease charac-terized by venous malformations of the skin and internal organs,affecting all systems throughout the body.The pathogenesis is unknown.There is no con-sensus on the treatment of BRBNS.Most of the previously reported cases were mild to moderate with a good prognosis,and this case was a critically ill patient with severe gastrointestinal hemorrhage,disseminated intravascular coagulation(DIC),and severe joint fusion that was different from previously reported cases.CASE SUMMARY An 18-year-old man with early onset of BRBNS in early childhood is reported.He presented with recurrent melena and underwent malformed phlebectomy and partial jejunectomy and ileal resection.The patient had melena before and after surgery.After active treatment,the patient's gastrointestinal bleeding improved.This was a case of atypical BRBNS with severe gastrointestinal bleeding and severe joint fusion,which should be differentiated from other serious joint lesions and provide clinicians with better understanding of this rare disease.CONCLUSION This case of critical BRBNS with gastrointestinal hemorrhage,DIC and severe joint fusion provides further understanding of this rare disease.

关 键 词：Blue rubber blister nevus syndrome Gastrointestinal hemorrhage Joint fusion Maffucci's syndrome Case report 

分 类 号：R656[医药卫生—外科学]