炎症及相关信号通路在动脉粥样硬化中的研究进展  

Advancements in the study of inflammation and associated signaling pathways in atherosclerosis

作　　者：张文鸿 崔璟 刘嘉敏 张燕[1] 洪志博 张宁坤 陈宇[1,2] ZHANG Wenhong;CUI Jing;LIU Jiamin;ZHANG Yan;HONG Zhibo;ZHANG Ningkun;CHEN Yu(Department of Cardiology,The Sixth Medical Center of Chinese People's Liberation,Army General Hospital,Beijing,100048,China;Navy Clinical College,The Fifth School of Clinical Medicine,Anhui Medical University)

机构地区：[1]解放军总医院第六医学中心,北京100048 [2]安徽医科大学第五临床医学院海军临床学院

出　　处：《临床心血管病杂志》2024年第10期845-852,共8页Journal of Clinical Cardiology

基　　金：国家重点研发计划(No:2022YFA1104300);北京市自然科学基金项目(No:7222183);安徽省研究生质量工程项目(No:2022xscx054)。

摘　　要：炎症被认为在动脉粥样硬化(atherosclerosis,AS)的发生和发展中扮演着关键角色。AS的抗炎治疗已经成为一种具有前景的治疗策略。本文详细探讨了AS与炎症及相关信号通路的关系,介绍了当前针对AS的抗炎治疗策略和未来的研究方向,为深入研究AS抗炎治疗提供参考。Inflammation is believed to play a pivotal role in the onset and progression of atherosclerosis(AS).Anti-inflammatory treatments for AS have emerged as a promising therapeutic strategy.This article delves into the relationship between AS and inflammatory,as well as associated signaling pathways.It also presents current anti-inflammatory treatment strategies for AS and directions for future research,serving as a reference for in-depth studies on anti-inflammatory treatments for atherosclerosis.

关 键 词：动脉粥样硬化 炎症 信号通路 生物标志物 抗炎治疗 

分 类 号：R541[医药卫生—心血管疾病]