探针式近红外自体荧光技术在术中甲状旁腺识别中的应用研究  

Application of near-infrared autofluorescence probe in intraoperative parathyroid gland identification

作　　者：花苏榕[1] 高俊义 曹桢 郑淮今 汪洪宇 宁小晶 傅丽元 张洋[3] 王贻坤[3] 刘子文[1] 廖泉[1] Hua Surong;Gao Junyi;Cao Zhen;Zheng Huaijin;Wang Hongyu;Ning Xiaojing;Fu Liyuan;Zhang Yang;Wang Yikun;Liu Ziwen;Liao Quan(Department of General Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of General Surgery,Beijing Dongcheng District Longfu Hospital,Beijing 100010,China;Anhui Institute of Optics and Fine Mechanics,Chinese Academy of Sciences,Hefei 230031,China)

机构地区：[1]中国医学科学院北京协和医学院、北京协和医院基本外科,北京100730 [2]北京市东城区隆福医院普通外科,北京100010 [3]中国科学院合肥物质科学研究院、安徽光学精密机械研究所,合肥230031

出　　处：《中华内分泌外科杂志（中英文）》2024年第5期675-678,共4页Chinese Journal of Endocrine Surgery

基　　金：中央高水平医院临床科研专项(2022-PUMCH-B-003);安徽省科技创新攻坚计划(202423110050013)。

摘　　要：目的探讨探针式近红外自体荧光技术(NIRAF-P)在术中识别甲状旁腺的应用价值。方法选取2023年12月至2024年6月在中国医学科学院北京协和医院基本外科、北京市隆福医院普通外科行甲状腺手术的68例,术中使用NIRAF-P识别待测甲状旁腺组织,并行病理组织学检查。分析NIRAF-P的识别阳性预测值和准确率。结果68例共识别待测甲状旁腺111枚,NIRAF-P识别阳性预测值和准确率分别为95.5%和94.6%。结论NIRAF-P识别甲状旁腺具有较高准确性,规范应用NIRAF-P有助于提升术中甲状旁腺的识别效率。ObjectiveTo explore the use of near-infrared autofluorescence probe(NIRAF-P)and its application in identifying parathyroid glands during surgery.MethodsA total of 68 patients undergoing thyroid surgery at Peking Union Medical College Hospital and Beijing Longfu Hospital between Dec.2023 and Jun.2024 were selected.During the operation,the near-infrared parathyroid gland detector was used to identify the parathyroid gland tissue to be tested,and histopathological examination was performed.The positive predictive value and accuracy of the near-infrared parathyroid gland detector were analyzed.ResultsA total of 111 parathyroid glands were identified in 68 patients,and the positive predictive value and accuracy of the NIRAF-P were 95.5%and 94.6%,respectively.ConclusionsThe NIRAF-P has high accuracy in identifying parathyroid glands.The standardized application of the NIRAF-P can help improve the efficiency of identifying parathyroid glands during surgery.

关 键 词：近红外自体荧光 甲状旁腺 甲状腺 

分 类 号：R653[医药卫生—外科学]