缩宫素注射液致严重过敏样反应1例分析  

One case of severe allergic reactions caused by oxytocin injection

作　　者：巨康璐 常瑛 刘振国 JU Kanglu;CHANG Ying;LIU Zhenguo(Department of Pharmacy,Northwest Women’s and Children’s Hospital,Xi’an Shaanxi 710061,China)

机构地区：[1]西北妇女儿童医院药剂科,陕西西安710061

出　　处：《中国药物警戒》2024年第10期1169-1171,共3页Chinese Journal of Pharmacovigilance

基　　金：陕西省重点研发计划(2024SF-YBXM-159)。

摘　　要：目的分析缩宫素注射液致严重过敏样反应的病例,为临床安全合理用药提供参考。方法分析1例稽留流产患者,在清宫术后使用缩宫素注射液连续用药第2天,在静脉滴注2 min后发生严重过敏样反应的病例,并进行文献回顾性分析,探讨其原因及防治措施。结果患者发生的严重过敏样反应很可能与缩宫素注射液有关,此类情况在临床比较少见。患者经有效的抗过敏治疗后,症状好转。结论临床应用缩宫素注射液时,需全程防范严重过敏样反应的发生,及早发现与处理。Objective To analyze severe allergic reactions caused by oxytocin injection so as to provide references for safe and rational drug use.Methods One rare case of severe allergic reactions in a patient with missed abortion was reported,who had manifested critical symptoms after two minutes of intravenous infusion of oxytocin on the second day of continuous injection.Related literature was retrospectively analyzed.The causes and preventive measures were studied.Results The severe allergic reactions were likely related to oxytocin injection,and such cases were very rare.The symptoms were relieved after effective anti-allergic treatment.Conclusion Clinicians need to prevent severe allergic reactions caused by oxytocin injection,and early detection and treatment are crucial.

关 键 词：缩宫素 注射液 严重过敏样反应 药品不良反应 

分 类 号：R979.2[医药卫生—药品] R994.11[医药卫生—药学]