多功能集成色谱-电感耦合等离子体质谱(ICP-MS)法快速测定饮用水中砷形态  

Rapid Determination of Arsenic Species in Drinking Water by Inductively Coupled Plasma Mass Spectrometry with Multifunctional Integrated Chromatography

作　　者：姜健 叶利萍 王晓玮[1] 谢继安[1] 单晓梅[1] 陈曦[3] JIANG Jian;YE Liping;WANG Xiaowei;XIE Ji′an;SHAN Xiaomei;CHEN Xi(Anhui Provincial Center for Disease Control and Prevention,Hefei,Anhui 230601,China;Shanghai Chemlab Pro Technology Co.,Ltd.,Shanghai 201306,China;National Institute of Environmental Health,Chinese Center for Disease Control and Prevention,Beijing 100050,China)

机构地区：[1]安徽省疾病预防控制中心,合肥230601 [2]上海凯来谱科技有限公司,上海201306 [3]中国疾病预防控制中心环境与健康相关产品安全所,北京100050

出　　处：《中国无机分析化学》2024年第12期1617-1623,共7页Chinese Journal of Inorganic Analytical Chemistry

基　　金：全国城市饮用水卫生监测项目(JCPJ01);2018年国家卫生健康委卫生标准制修订项目(20180901)。

摘　　要：为准确快速测定饮用水中砷形态,采用多功能集成色谱(prepFAST IC)与电感耦合等离子体质谱(ICP-MS)联用,采用ICX-As35阴离子色谱柱为分析柱,通过仪器注射器推动改变1 mmol/L碳酸铵(pH=9.7)和100 mmol/L碳酸铵(pH=9.2)洗脱液的混合比,进行浓度梯度洗脱,在105 s内快速分析出甜菜碱(AsB)、亚砷酸盐[As(Ⅲ)]、二甲基砷(DMA)、砷胆碱(AsC)、一甲基砷(MMA)和砷酸盐[As(V)]六种As的形态,建立饮用水中六种砷(As)形态的多功能集成色谱串联ICP-MS分析方法。在0~100μg/L六种As的形态线性关系良好,相关系数均大于0.999,检出限为0.02~0.03μg/L。采用加标回收进行准确性评估,纯水和末梢水低、中、高浓度样本的加标回收率为89.2%~103%,不同浓度砷形态的相对标准偏差(RSD)均优于2.0%。方法灵敏度高、准确可靠、分析效率高,适用于生活饮用水中砷形态的快速测定,提高了工作效率。In order to accurately and rapidly determine arsenic speciation in drinking water,a method of six arsenic species in drinking water by inductively coupled plasma mass spectrometry(ICP-MS)with multifunctional integrated chromatography was developed.The multifunctional integrated chromatography(prepFAST IC)was coupled with inductively coupled plasma mass spectrometry(ICP-MS),and the ICX-As35 anion chromatography column was used as the analytical column.The concentration gradient elution was performed by pushing the mixing ratio of 1 mmol/L ammonium carbonate(pH=9.7)and 100 mmol/L ammonium carbonate(pH=9.2)eluent through the syringe of the instrument to change the mixture ratio of the eluent.Six arsenic species,betaine(AsB),arsenite[As(Ⅲ)],dimethylarsenic(DMA),arsenicholine(AsC),monomethylarsenic(MMA)and arsenate[As(V)],were analyzed within 105 s.The linearity of the six arsenic species was good in the range of 0-100μg/L with the correlation coefficients(r)greater than 0.999,and the limits of detection(LODs)were 0.02—0.03μg/L.The relative standard deviations(RSD)of arsenic species in pure water and tap water were all no more than 2.0%.The recoveries of three different concentrations in pure water and tap water ranged from 89.2%to 103%.This method is accurate,reliable,sensitive,short analysis time,and suitable for the rapid determination of drinking water,improving the working efficiency.

关 键 词：多功能集成色谱 电感耦合等离子体质谱 快速测定 砷形态 生活饮用水 

分 类 号：O657.63[理学—分析化学] R115[理学—化学] R123[医药卫生—公共卫生与预防医学]