点阵CO_(2)激光术后皮肤屏障修复的研究进展  

Advances in skin barrier repair after fractional carbon dioxide laser surgery

作　　者：任浩 邱湘宁[1] 谭怡忻[1] 肖嵘[1] REN Hao;QIU Xiangning;TAN Yixin;XIAO Rong(Department of Dermatology,Second Xiangya Hospital of Central South Universty,Changsha 410000,China)

机构地区：[1]中南大学湘雅二医院皮肤性病科,湖南长沙410000

出　　处：《中国美容整形外科杂志》2024年第10期595-600,615,共7页Chinese Journal of Aesthetic and Plastic Surgery

基　　金：国家自然科学基金(82373486)。

摘　　要：点阵CO_(2)激光已广泛应用于皮肤激光美容领域中,并取得显著的临床治疗效果,常与其他治疗方法联合协同作用或助力药物输送,从而进一步强化疗效。然而,不容忽视的是,点阵CO_(2)激光在治疗的同时也伴随着皮肤屏障结构的破坏及功能的损伤,常表现为红斑、水肿、皮肤干燥和炎症后色素沉着(postinflammatory hyperpigmentation,PIH)等不良反应。因此,临床医师需要高度重视点阵CO_(2)激光治疗后的皮肤屏障修复,针对患者表现出不同的皮肤问题,需要个性化调整点阵CO_(2)激光治疗的参数,并结合最新的研究成果,如多肽、多糖、富血小板血浆(platelet-rich plasma,PRP)及其衍生物等,以制定更加完善的皮肤屏障修复方案。Fractional CO_(2) laser has a wide range of clinical applications and remarkable therapeutic effects in the field of skin laser aesthetics,and is often synergized with other treatments or assisted by drug delivery to further strengthen the therapeutic effects.However,it should not be ignored that fractional CO_(2) laser treatment is also accompanied by damage to the skin barrier structure and function,often manifested as erythema,edema,dry skin and post-inflammatory hyperpigmentation and other adverse reactions.Therefore,clinicians need to pay great attention to post-procedure skin barrier repair of fractional CO_(2) laser.For different skin problems,clinicians need to individually adjust the treatment parameters of fractional laser and combine the latest research results,such as peptides,polysaccharides,PRP and low-dose laser technology,in order to formulate a more perfect skin barrier repair program.

关 键 词：点阵CO_(2)激光 美学应用 皮肤屏障 修复 

分 类 号：R622[医药卫生—整形外科]