Ti3C2Tx MXene-functionalized Hydroxyapatite/Halloysite nanotube filled poly-(lactic acid)coatings on magnesium:In vitro and antibacterial applications  

作　　者：Mehmet Topuz Yuksel Akinay Erkan Karatas Tayfun Cetin 

机构地区：[1]Department of Mechanical Engineering,Van Yuzuncu Yil University,Van 65080,Turkey [2]Department of Mining Engineering,Van Yuzuncu Yil University,Van,65080,Turkey [3]Department of Molecular Biology and Genetics,Erzurum Technical University,Erzurum 25100,Turkey [4]Yuksekova Vocational High School,Hakkari University,Hakkari 30110,Turkey

出　　处：《Journal of Magnesium and Alloys》2024年第9期3758-3771,共14页镁合金学报（英文）

摘　　要：Magnesium(Mg)stands out in temporary biomaterial applications due to its biocompatibility,biodegradability,and low Young’s modulus.However,controlling its corrosion through next-generation polymer-based functional coatings is crucial due to the rapid degradation behavior of Mg.In this study,the function of 2D lamellar Ti_(3)C_(2)T_(x)(MXene)in Hydroxyapatite(HA)and Halloysite nanotube(HNT)hybrid coatings in biodegradable poly-(lactic acid)(PLA)was investigated.The morphological and structural characterizations of the coatings on Mg were revealed through HRTEM,XPS,SEM-EDX,XRD,FTIR,and contact angle analyses/tests.Electrochemical in vitro corrosion tests(OCP,PDS,and EIS-Nyquist)were conducted for evaluate corrosion resistance under simulated body fluid(SBF)conditions.The bioactivity of the coatings in SBF have been revealed in accordance with the ISO 23,317 standard.Finally,antibacterial disk diffusion tests were conducted to investigate the functional effect of MXene in coatings.It has been determined that the presence of MXene in the coating increased not only surface wettability(131°,85°,77°,and 74°for uncoated,pH,PHH,and PHH/MXene coatings,respectively)but also increased corrosion resistance(1857.850,42.357,1.593,and 0.085×10^(-6),A/cm^(2) for uncoated,pH,PHH,and PHH/MXene coatings,respectively).It has been proven that the in vitro bioactivity of PLA-HA coatings is further enhanced by adding HNT and MXene,along with SEM morphologies after SBF.Finally,2D lamellar MXene-filled coating exhibits antibacterial behavior against both E.coli and S.aureus bacteria.

关 键 词：MAGNESIUM Pla coating Ti3c2tx mxene In-vitro bioactivity Disk diffusion 

分 类 号：TG174.4[金属学及工艺—金属表面处理]