微塑料和纳米塑料对心脏的影响及机制研究进展  

The impacts of micro-and-nano plastics on heart

作　　者：王菁菁 黄观明 冯灿(综述) 崔海明(审校) Wang Jingjing;Huang Guanming;Feng Can;Cui Haiming(Department of Cardiology,The Affiliated Hospital of Shanghai University of Traditional Chinese Medicine,Yueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine,Shanghai 200080,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院心内科,上海200080

出　　处：《疑难病杂志》2024年第11期1390-1393,共4页Chinese Journal of Difficult and Complicated Cases

基　　金：国家中医药管理局高水平中医药重点学科建设项目(zyyzdxk-2023065);上海市科学技术委员会科研计划项目(19DZ1930404,21JC1405300)。

摘　　要：微塑料和纳米塑料(MNPs)可通过摄入、吸入和皮肤接触等多种方式进入人体。相关研究发现MNPs对心脏具有多方面影响,包括心律失常、心包水肿、心功能受损等,同时研究发现与其他污染物共同暴露时不良反应比单一暴露更小。文章就MNPs对心脏的影响进行综述,为未来针对MNPs引起的相关危害制定治疗方案和探索利用MNPs进行疾病诊断和治疗提供思路。Microplastics and nanoplastics(MNPs)widely exist in food,water,air and daily necessities,and humans may be exposed through intake,inhalation and skin contact.Studies have found that MNPs has many effects on the heart,including arrhythmia,pericardial edema,impaired cardiac function,etc.Even when it is exposed with other pollutants,the adverse reaction is less than that of single exposure.This paper reviews the effects of MNPs on the heart,so as to provide ideas for making therapeutic decision of diseases related to MNPs and exploring the use of MNPs for disease diagnosis and treatment in the future.

关 键 词：微塑料 纳米塑料 心血管疾病 心律失常 心包水肿 心功能受损 

分 类 号：R994.6[医药卫生—毒理学]