2例双重滤过血浆置换治疗白血病患者严重铁过载报道及文献复习  

Leukemia patients with severe iron overload and treated with double filtration plasmapheresis:report of two cases and review of the literature

作　　者：宋佚凡 陈利婷 张超 任野萍 王琴 SONG Yi-Fan;CHEN Li-ting;ZHANG Chao;REN Ye-ping;WANG Qin(Department of Nephrology,Shenzhen University General Hospital,Shenzhen 518055,China)

机构地区：[1]深圳大学总医院肾脏病科,深圳518055

出　　处：《中国血液净化》2024年第11期878-880,共3页Chinese Journal of Blood Purification

基　　金：国家自然科学基金面上项目(82270774)。

摘　　要：报道2例使用双重滤过血浆置换(double filtration plasmapheresis,DFPP)治疗白血病患者严重铁过载,治疗后铁蛋白显著降低且未见严重不良反应。提示DFPP可能是严重铁过载时快速清除铁蛋白的方法,可以用于祛铁药物治疗欠佳或药物不耐受的铁过载患者。We report two leukemia patients with severe iron overload and successfully treated with double filtration plasmapheresis(DFPP).After the treatment,serum ferritin reduced significantly without any severe complications.We suggest that DFPP is a fast and efficient therapy to remove ferritin,and can be used in severe iron overload patients with poor response or intolerance to drug treatment.

关 键 词：双重滤过血浆置换 铁过载 白血病 

分 类 号：R459.5[医药卫生—治疗学]