右美托咪定静脉泵注联合七氟醚吸入麻醉在老年膝骨关节炎手术患者中的应用效果分析  

Analysis of the Application Effect of Intravenous Infusion of Dexmedetomidine Combined with Sevoflurane Inhalation Anesthesia in Elderly Patients Undergoing Knee Osteoarthritis Surgery

作　　者：周清吉 ZHOU Qingji(Department of Anesthesiology,Fuqing Third Hospital,Fuzhou,Fujian,350301,China)

机构地区：[1]福清市第三医院麻醉科,福建福州350301

出　　处：《中外医疗》2024年第29期126-129,共4页China & Foreign Medical Treatment

摘　　要：目的探讨手术治疗骨关节炎老年患者时应用七氟醚吸入麻醉与右美托咪定结合的麻醉效果。方法本研究为前瞻性研究,随机选取2020年10月—2023年10月福清市第三医院行膝骨关节炎手术治疗的200例老年患者为研究对象,依据不同麻醉方法分为两组,每组100例。两组患者采取相同的麻醉诱导药物方案,对照组维持麻醉方案是七氟醚吸入,观察组维持麻醉方案是七氟醚吸入+右美托咪定静脉泵注。对比两组患者麻醉相关指标、术中不同节点生命体征、麻醉不良反应发生情况。结果观察组麻醉苏醒时间为(8.46±2.26)min、拔除气管插管时间为(13.56±3.71)min、呼吸恢复时间为(10.16±2.52)min、苏醒期躁动评分为(3.12±0.64)分,均低于对照组的(11.43±3.55)min、(18.72±3.68)min、(13.57±2.34)min、(4.13±0.81)分,差异有统计学意义(t=7.057、9.874、9.915、9.783,P均<0.05)。相比于对照组,观察组术中不同节点生命体征的变化更稳定,差异有统计学意义(P均<0.05)。观察组麻醉不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论膝骨关节炎老年患者在手术治疗时采取七氟醚吸入联合右美托咪定麻醉可维持术中生命体征稳定,缩短麻醉苏醒时间,降低苏醒期躁动评分,减少麻醉不良反应的发生。Objective To study the effect of sevoflurane inhalation anesthesia combined with dexmedetomidine during surgical anesthesia in elderly patients with knee osteoarthritis.Methods The study was conducted in a prospective manner,a total of 200 elderly patients who underwent surgery for knee osteoarthritis in the Fuqing Third Hospital from October 2020 to October 2023 were randomly selected as the study objects and divided into two groups according to different anesthesia methods,with 100 cases in each group.The two groups were treated with the same anesthesia in⁃duction drug regimen.The control group was treated with sevoflurane inhalation,while the observation group was treated with sevoflurane inhalation plus dexmedetomidine intravenously.Anesthesia-related indexes,vital signs at dif⁃ferent points during operation,and the occurrence of anesthesia adverse reactions were compared between the two groups.Results In the observation group,the time of anesthesia recovery was(8.46±2.26)min,the time of tracheal in⁃tubation removal was(13.56±3.71)min,the time of respiratory recovery was(10.16±2.52)min,and the score of agita⁃tion during recovery was(3.12±0.64)points,which were all lower than(11.43±3.55)min,(18.72±3.68)min,(13.57±2.34)min,(4.13±0.81)points in the control group,and the differences were statistically significant(t=7.057,9.874,9.915,9.783,all P<0.05).Compared with the control group,the changes of vital signs at different nodes in the obser⁃vation group were more stable,and the differences were statistically significant(all P<0.05).The incidence of anesthe⁃sia adverse reactions in observation group was lower than that in control group,and the difference was statistically sig⁃nificant(P<0.05).Conclusion Sevoflurane inhalation combined with dexmedetomidine can maintain the stability of vi⁃tal signs,shorten the time of anesthesia recovery,reduce the score of agitation during anesthesia,and reduce the oc⁃currence of anesthesia adverse reactions in elderly patients with knee osteoarthritis.

关 键 词：老年膝骨关节炎 七氟醚吸入麻醉 右美托咪定 生命体征 并发症 

分 类 号：R684.3[医药卫生—骨科学]