Spacem占位器专用骨水泥联合敏感抗生素在全膝关节置换术后感染二期翻修中的应用效果  

Application Effect of Spacem Space Occupying Device Specific Bone Cement Combined with Sensitive Antibiotics in the Second Phase Revision of Infection after Total Knee Arthroplasty

作　　者：宋维 杨武镠 刘泉 李洋 SONG Wei;YANG Wuliu;LIU Quan;LI Yang(Department of OrthopedicsⅠ,Qianxi People's Hospital,Qianxi 551500,Guizhou,China)

机构地区：[1]黔西市人民医院骨一科,贵州黔西551500

出　　处：《世界复合医学（中英文）》2024年第9期120-123,共4页World Journal of Complex Medicine

摘　　要：目的探讨全膝关节置换术后感染二期翻修中应用敏感抗生素联合Spacem占位器专用骨水泥治疗的效果。方法选择2022年1月—2023年12月黔西市人民医院收治的60例全膝关节置换术后感染患者作为研究对象,根据治疗方法的不同将其分为对照组和观察组,各30例。对照组采用传统方法治疗,观察组采用Spacem占位器专用骨水泥联合敏感抗生素治疗。比较两组炎症指标、临床疗效和术后并发症总发生率。结果治疗前,两组患者白细胞计数、中性粒细胞比例对比,差异无统计学意义(P均>0.05)。治疗后,观察组患者白细胞计数为(5.74±0.83)×10~9/L,中性粒细胞比例为(42.34±2.05)%,低于对照组的(12.01±1.26)×10~9/L、(68.11±2.27)%,差异有统计学意义(t=8.254、9.361,P均<0.05)。观察组治疗总有效率高于对照组,术后并发症总发生率低于对照组,差异有统计学意义(P均<0.05)。结论Spacem占位器专用骨水泥联合敏感抗生素在全膝关节置换术后感染二期翻修中的应用效果显著,且安全性高。Objective To explore the effectiveness of using sensitive antibiotics combined with Spacem space occupying device specific bone cement in the second phase revision of infection after total knee arthroplasty.Methods From January 2022 to December 2023,60 patients with infection after total knee arthroplasty admitted to Qianxi People's Hospital were selected as the research objects.They were divided into control group and observation group according to different treatment methods,30 cases in each group.The patients in the control group were treated with traditional methods,and the patients in the observation group were treated with Spacem space occupying device specific bone cement combined with sensitive antibiotics.The inflammatory indicators,clinical efficacy and total incidence of postoperative complications were compared between the two groups.Results Before treatment,there was no significant difference in white blood cell count and neutrophil ratio between the two groups(both P>0.05).After treatment,the white blood cell count of the observation group was(5.74±0.83)×109/L,and the proportion of neutrophils was(42.34±2.05)%,which were lower than(12.01±1.26)×109/L,(68.11±2.27)%of the control group,and the differences were statistically significant(t=8.254,9.361,both P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group,and the total incidence of postoperative complications was lower than that in the control group,and the differences were statistically significant(both P<0.05).Conclusion The application of Spacem space occupying device specific bone cement combined with sensitive antibiotics in the second phase revision of infection after total knee arthroplasty is significant and safe.

关 键 词：全膝关节置换术后感染 Spacem占位器 骨水泥 敏感抗生素 二期翻修 

分 类 号：R68[医药卫生—骨科学]