尿常规与尿微量白蛋白检测在糖尿病早期肾损伤中的诊断价值  

Diagnostic Value of Urine Routine Examination and Urine Microalbumin Detection in Early Diabetic Kidney Injury

作　　者：余联多 YU Lianduo(Department of Clinical Laboratory,Datian County General Hospital,Sanming 366100,Fujian,China)

机构地区：[1]大田县总医院检验科,福建三明366100

出　　处：《糖尿病新世界》2024年第16期63-66,共4页Diabetes New World

摘　　要：目的分析尿常规、尿微量白蛋白对糖尿病早期肾损伤的诊断价值。方法选取2021年1月—2024年2月大田县总医院收治的179例糖尿病早期肾损伤患者为观察组,同时筛选180例单纯糖尿病患者为对照组,两组均给予尿常规与尿微量白蛋白检测,以临床诊断结果为金标准,统计尿常规、尿微量白蛋白单独诊断与联合诊断的结果,并计算诊断效能。结果尿常规检出阳性131例,阴性228例;尿微量白蛋白检出阳性154例,阴性205例;尿常规与尿微量白蛋白联合检出阳性182例,阴性177例。尿常规与尿微量白蛋白联合检测的准确度、特异度、灵敏度、阳性预测值、阴性预测值均高于尿常规、尿微量白蛋白单独检测,差异有统计学意义(P均<0.05)。结论在糖尿病早期肾损伤的临床诊断中,尿常规和尿微量白蛋白均能在一定程度上检测出肾功能异常,但两者结合可实现更高的诊断效能,实现早发现、早诊断、早治疗,有利于有效改善患者预后。Objective To investigate the diagnostic value of urine routine and urine microalbumin in the diagnosis of early diabetic kidney injury.Methods A total of 179 patients with early diabetic kidney injury admitted to Datian County General Hospital from January 2021 to February 2024 were selected as the observation group,while 180 patients with simple diabetes were selected as the control group.Both groups were given urine routine and urine microal-bumin detection.The clinical diagnosis results were used as the gold standard.The results of urine routine,urine microalbumin single diagnosis and combined diagnosis were counted,and the diagnostic efficacy was calculated.Results Urine routine detection was positive in 131 cases and negative in 228 cases.Urine microalbumin was positive in 154 cases and negative in 205 cases.Urine routine and microalbumin were positive in 182 cases and negative in 177 cases.The accuracy,specificity,sensitivity,positive predictive value and negative predictive value of urine routine and urine microalbumin combined detection were higher than those of urine routine and urine microalbumin alone,and the differences were statistically significant(all P<0.05).Conclusion In the clinical diagnosis of early diabetic kid-ney injury,both urine routine and urinary microalbumin can detect renal function abnormalities to a certain extent,but the combination of the two can achieve higher diagnostic efficiency,early identification,early diagnosis and early treatment,which is conducive to effectively improving the prognosis of patients.

关 键 词：糖尿病早期肾损伤 尿常规 尿微量白蛋白 诊断 

分 类 号：R587.2[医药卫生—内分泌]