小剂量丙泊酚、舒芬太尼复合右美托咪定对宫腔镜手术患者镇静及睡眠质量的影响  

The Impact of Low-dose Propofol,Sufentanil Combined with Dexmedetomidine on Sedation and Sleep Quality in Patients Undergoing Hysteroscopic Surgery

作　　者：段宗伟 黄海玲 DUAN Zongwei;HUANG Hailing(Xiamen Anbao Hospital,Xiamen 361000,China;不详)

机构地区：[1]厦门安宝医院,福建厦门361000

出　　处：《中外医学研究》2024年第31期9-13,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:评估小剂量丙泊酚、舒芬太尼复合右美托咪定在宫腔镜手术中的麻醉效果及对患者术后睡眠质量的影响。方法:选择2022年7月—2023年7月厦门安宝医院收治的280例宫腔镜手术患者,根据随机双盲对照原则分为对照组和试验组,各140例。对照组接受丙泊酚和舒芬太尼麻醉,试验组接受右美托咪定、舒芬太尼和小剂量丙泊酚麻醉。记录并比较两组在麻醉诱导前(T_(0))、麻醉诱导后(T_(1))、扩宫颈时(T_(2))、苏醒时(T_(3))的心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2),以及手术时间、苏醒时间、苏醒后镇静状况(Ramsay)评分和视觉模拟评分法(VAS)评分。使用阿森斯失眠量表(AIS)评分评估两组患者的术前、术后第1天和第3天的睡眠状况,并记录不良反应发生状况。结果:两组不同时间HR对比,差异无统计学意义(P>0.05);试验组T_(1)、T_(2)、T_(3)时的MAP高于对照组,试验组在T1时SpO_(2)高于对照组,差异有统计学意义(P<0.05);两组手术时间对比,差异无统计学意义(P>0.05),试验组苏醒时间短于对照组,Ramsay评分和VAS评分低于对照组,差异有统计学意义(P<0.05);试验组术后第1天和第3天的AIS评分低于对照组,不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论:宫腔镜手术中使用右美托咪定、舒芬太尼和小剂量丙泊酚的麻醉方法能有效提高患者的镇静和镇痛效果,缩短手术时间和苏醒时间,改善术后睡眠质量,减少不良反应的发生。Objective:To evaluate the anesthetic effect of low-dose Propofol,Sufentanil combined with Dexmedetomidine during hysteroscopic surgery and its impact on postoperative sleep quality of patients.Method:A total of 280 patients with hysteroscopic surgery treated in Xiamen Anbao Hospital from July 2022 to July 2023 were selected and divided into control group and experimental group according to the principle of random double-blind control,with 140 cases in each group.The control group received Propofol and Sufentanil anesthesia,and the experimental group received Dexmedetomidine,Sufentanil and low-dose Propofol anesthesia.The heart rate(HR),mean arterial pressure(MAP),blood oxygen saturation(SpO_(2))before anesthesia induction(T_(0)),after anesthesia induction(T_(1)),during cervical dilation(T_(2)),and after recovery(T_(3)),operation time,recovery time,post-recovery sedation(Ramsay)score and visual analog scale(VAS)score of the two groups were recorded and compared.The Athens insomnia scale(AIS)score was used to evaluate the sleep status of the two groups before surgery,the first day and the third day after surgery,and the occurrence of adverse reactions was recorded.Result:There was no significant difference in HR between the two groups at different time(P>0.05).MAP of experimental group at T_(1),T_(2)and T_(3)were higher than those of control group,SpO_(2)of experimental group at T_(1)was higher than that of control group,the difference was statistically significant(P<0.05).There was no significant difference in the operation time between the two groups(P>0.05).The recovery time of the experimental group was shorter than that of the control group,and the Ramsay score and VAS score of the experimental group were lower than that of the control group,the differences were statistically significant(P<0.05).The AIS scores of the experimental group on the first and third days after surgery were lower than those of the control group,and the total incidence of adverse reactions was lower,the differences were statistically si

关 键 词：右美托咪定 舒芬太尼 丙泊酚 宫腔镜手术 镇静 

分 类 号：R614[医药卫生—麻醉学]