肌少症与外周动脉疾病关系的研究进展  

Research Progress on Relationship between Sarcopenia and Peripheral Arterial Disease

作　　者：邓偲婕 王晓茜[1] DENG Sijie;WANG Xiaoqian(Deyang People's Hospital,Deyang 618000,China;不详)

机构地区：[1]德阳市人民医院,四川德阳618000

出　　处：《中外医学研究》2024年第31期179-184,共6页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：德阳市科技计划重点研发项目(2021SZZ076)。

摘　　要：外周动脉疾病(PAD)是日益突出的全球公共问题,PAD患者易发生包括心脑血管意外、截肢、死亡等不良结局。肌少症,一种以肌肉量减少、肌肉力量下降及躯体功能减退为主要特征的新型老年综合征,与PAD存在一定程度的相关性。两者存在共同的危险因素及病理生理机制。肌少症在PAD中患病率较高,且与PAD的不良预后密切相关。因此,肌少症可能作为评判PAD预后的一个重要指标。对PAD患者进行早期肌少症筛查可能对临床治疗决策具有重要价值。目前关于PAD患者肌少症的评估及治疗研究还相对较少,缺乏相关指南共识,未来的研究需要更多关注这一领域,并据此优化PAD患者的综合性管理措施。Peripheral arterial disease(PAD)is an increasingly prominent global public health issue.Patients with PAD are prone to adverse outcomes,including cardiovascular and cerebrovascular incidents,amputation,and death.Sarcopenia,a novel geriatric syndrome characterized by reduced muscle mass,declining muscle strength,and decreased physical function,shows a certain degree of correlation with PAD.Both conditions share common risk factors and pathophysiological mechanisms.The prevalence of sarcopenia is higher in PAD patients and is closely related to poor prognoses in PAD.Therefore,sarcopenia may serve as an important indicator for assessing the prognosis of PAD.Early screening for sarcopenia in PAD patients could be of significant value for clinical treatment decisions.Currently,research on the assessment and treatment of sarcopenia in PAD patients is relatively scarce and lacks a consensus in guidelines.Future studies need to focus more on this area to improve the comprehensive management strategies for PAD patients.

关 键 词：外周动脉疾病 肌少症 动脉粥样硬化 评估 治疗 

分 类 号：R543.5[医药卫生—心血管疾病]