脑血管病急性期患者采用化瘀通络汤治疗的效果分析  

Analysis of the effect of Huayu Tongluo decoction for patients with acute cerebrovascular disease

作　　者：李大庆 LI Da-qing(Lianyungang Ganyu District Hospital of Traditional Chinese Medicine,Lianyungang 222100,China)

机构地区：[1]连云港市赣榆区中医院,222100

出　　处：《中国实用医药》2024年第20期145-148,共4页China Practical Medicine

摘　　要：目的分析对脑血管病急性期患者采用化瘀通络汤治疗的临床效果。方法选取110例脑血管病急性期患者,按全盲抓阄法分为对照组和观察组,各55例。对照组采用常规西医治疗,观察组采取化瘀通络汤治疗。对比两组中医证候积分、美国国立卫生研究院卒中量表(NIHSS)评分、血液流变学指标、血清因子及临床疗效、不良反应发生情况。结果治疗后,观察组中医证候积分(9.82±5.42)分、NIHSS评分(9.47±4.03)分均低于对照组的(13.58±5.14)、(14.62±4.27)分(P<0.05)。治疗后,观察组全血高切粘度(3.95±0.67)mPa·s、全血低切粘度(4.13±1.03)mPa·s、红细胞压积(41.82±3.52)%、纤维蛋白原(2.36±0.19)g/L明显低于对照组的(5.08±0.52)mPa·s、(5.37±1.36)mPa·s、(48.63±4.07)%、(3.43±0.24)g/L(P<0.05)。治疗后,观察组血管内皮生长因子(VEGF)水平为(349.86±52.72)ng/L、血清碱性成纤维细胞生长因子(BFGF)水平为(20.94±6.38)pg/ml,均高于对照组的(279.67±34.57)ng/L、(14.29±3.36)pg/ml(P<0.05)。观察组总有效率98.18%高于对照组的81.82%(P<0.05)。两组均未发生不良反应。结论对脑血管病急性期患者采用化瘀通络汤进行治疗能够使临床症状得到改善,提高临床治疗效果,且无不良反应发生。Objective To analyze the clinical effect of Huayu Tongluo decoction for patients with acute cerebrovascular disease.Methods 110 patients with acute cerebrovascular disease were selected and divided into a control group and an observation group according to the blind lottery method,each consisting of 55 patients.The control group received routine Western medicine treatment,while the observation group received Huayu Tongluo decoction treatment.The traditional Chinese medicine syndrome score,National Institutes of Health Stroke Scale(NIHSS)score,hemorheology index,serum factor,clinical efficacy and occurrence of adverse reactions were compared between the two groups.Results After treatment,the traditional Chinese medicine syndrome score of the observation group was(9.82±5.42)points and NIHSS score was(9.47±4.03)points,which were lower than(13.58±5.14)and(14.62±4.27)points of the control group(P<0.05).After treatment,in the observation group,the whole blood high-shear viscosity was(3.95±0.67)mPa·s,the whole blood low-shear viscosity was(4.13±1.03)mPa·s,the hematocrit was(41.82±3.52)%,and the fibrinogen was(2.36±0.19)g/L,which were significantly lower than(5.08±0.52)mPa·s,(5.37±1.36)mPa·s,(48.63±4.07)%,and(3.43±0.24)g/L in the control group(P<0.05).After treatment,the observation group had vascular endothelial growth factor(VEGF)level of(349.86±52.72)ng/L,and serum basic fibroblast growth factor(BFGF)level of(20.94±6.38)pg/ml,which were higher than(279.67±34.57)ng/L and(14.29±3.36)pg/ml in the control group(P<0.05).The total effective rate of 98.18%in the observation group was higher than 81.82%in the control group(P<0.05).No adverse reactions occurred in both groups.Conclusion The use of Huayu Tongluo decoction for the treatment of acute cerebrovascular disease patients can improve their clinical symptoms,improve the effect of clinical treatment,and have no adverse reactions.

关 键 词：化瘀通络汤 脑血管病急性期 临床疗效 

分 类 号：R277.7[医药卫生—中医学]