基于三维超声技术分析传统心血管危险因素与动脉粥样硬化相关心力衰竭患者斑块体积的关系  

Relationship between traditional cardiovascular risk factors and plaque volume in patients heart failure with atherosclerotic based on three-dimensional ultrasound technology

作　　者：李苏明 孙晓艳[2] 段秉慧 郭守玉[2] LI Suming;SUN Xiaoyan;DUAN Binghui;GUO Shouyu(Department of Ultrasound,the First Hospital of Anhui University of Science and Technology of Huainan,Huainan Anhui 232000,China)

机构地区：[1]安徽理工大学第一附属医院超声科,安徽淮南232000 [2]南京医科大学第二附属医院心血管内科,江苏南京210011

出　　处：《中国急救复苏与灾害医学杂志》2024年第11期1405-1408,共4页China Journal of Emergency Resuscitation and Disaster Medicine

基　　金：国家卫生健康委医药卫生科技发展研究中心(编号:WKZX2022JG0122)。

摘　　要：目的 本研究使用三维超声方法测量动脉粥样硬化相关心力衰竭患者的颈动脉和股动脉斑块体积,并分析传统心血管风险因素(CVRF)与斑块体积的关系。方法 本研究纳入2022年5月—2024年3月安徽理工大学第一附属医院确诊的动脉粥样硬化相关心力衰竭患者,共248例。使用配备自动化软件三维超声测定所有受试者的颈动脉和股动脉斑块体积,通过统计学分析斑块体积与传统CVRF的关系。结果 入组患者斑块总体积的中位数为167 mm^(3),将患者分为低斑块总体积组(≤167 mm^(3))和高斑块总体积组(>167 mm^(3))进行分析;高斑块总体积组中存在高血压、吸烟和心血管疾病家族史患者比例显著高于低斑块总体积组(P<0.05)。通过统计患者的传统心血管危险因素,并将其分为CVRF=1组(n=41)、CVRF=2组(n=48)和CVRF≥3组(n=123),CVRF≥3 CVRF组的总斑块体积、颈动脉斑块体积、股动脉斑块体积明显高于CVRF=2组与CVRF=1组,差异有统计学意义(P<0.05)。多变量预测模型中,高血压、吸烟、糖尿病、高脂血症和心血管疾病家族史与斑块体积呈显著正相关(P<0.05)。结论 应用三维超声评估动脉粥样硬化相关心力衰竭患者的斑块体积发现,斑块体积与高血压、吸烟、糖尿病、高脂血症和心血管疾病家族史呈正相关,且随CVRF数量的增加,总斑块、颈动脉斑块和股动脉斑块体积显著增加。Objective This study aimed to measure the plaque volume of carotid and femoral arteries in patients with atherosclerotic heart failure using three-dimensional ultrasound (3D-US) and analyze the relationship between traditional cardiovascular risk factors (CVRF) and plaque volume.Methods A total of 248 patients with atherosclerotic heart failure diagnosed in the First Hospital of Anhui University of Science and Technology from May2022 to March 2024 were included in this study.Carotid and femoral artery plaque volumes were determined in all subjects using 3D ultrasound equipped with automated software,and the relationship between plaque volume and conventional CVRF was statistically analysed.Results The median total plaque volume of the enrolled patients was167 mm~3,and the patients were divided into the low total plaque volume group (≤167 mm~3) and the high total plaque volume group (>167 mm~3) for analysis;the number of patients with hypertension,smoking,and a family history of cardiovascular disease in the high total plaque volume group was significantly higher than that in the low total plaque volume group (P<0.05).The traditional cardiovascular risk factors in patients were counted divided into CVRF=1group(n=41),CVRF=2 group(n=84),CVRF≥3 group(n=123)2 CVRF,and≥3 CVRF.The total plaque volume,carotid plaque volume and femoral artery plaque volume in CVRF≥3 group were significantly higher than those in CVRF=2 group and CVRF=1 group.In the multivariate prediction model,CVRFs such as hypertension,smoking,diabetes mellitus,hyperlipidemia,and family history of cardiovascular disease were significantly and positively associated with plaque volume (P<0.05).Conclusion Application of three-dimensional ultrasound to assess plaque volume in patients with atherosclerotic heart failure revealed a significant positive correlation between plaque volume and hypertension,smoking,diabetes mellitus,hyperlipidemia,and family history of cardiovascular disease in patients with atherosclerotic heart failure,as well as a signif

关 键 词：动脉粥样硬化 三维超声检测 动脉粥样硬化伴心力衰竭 传统心血管危险因素 

分 类 号：R543.5[医药卫生—心血管疾病]