高通量血液透析疗法对糖尿病肾病患者Ccr、BUN等指标的影响研究  

Effect Research on High Flux Hemodialysis Therapy for Ccr,BUN and Other Indicators of Patients with Diabetes Nephropathy

作　　者：姚祥云 张建国 YAO Xiangyun;ZHANG Jianguo(Gong'an County Traditional Chinese Medicine Hospital,Jingzhou,Hubei 434300)

机构地区：[1]公安县中医医院,湖北荆州434300

出　　处：《智慧健康》2024年第20期25-27,46,共4页Smart Healthcare

摘　　要：目的分析高通量血液透析疗法对糖尿病肾病患者肌酐清除率(Ccr)、尿素氮(BUN)等指标的影响。方法将2021年5月—2022年4月本院收治的80例糖尿病肾病患者纳入研究,采取随机数字表法将其分为研究组和对照组,每组40例。研究组采取高通量血液透析疗法,对照组采取低通量血液透析疗法。对比两组肾功能指标、炎性因子、血糖相关及胰岛素指标。结果治疗后,研究组的Ccr较对照组更高,BUN和Scr值较对照组更低(P<0.05);研究组的炎症因子较对照组更低(P<0.05);研究组血糖相关及胰岛素水平较对照组更低(P<0.05)。结论将高通量血液透析疗法应用于糖尿病肾病患者的治疗中,可改善其肾功能,减轻炎症反应,降低血糖水平,值得临床推广应用。Objective To analyze the effects of high throughput hemodialysis therapy on creatinine clearance(Ccr),urea nitrogen(BUN)and other indexes in diabetic nephropathy patients.Methods 80 patients with diabetic nephropathy admitted to our hospital from May 2021 to April 2022 were randomly divided into study group and control group with 40 cases in each group.The study group was provided with highflux hemodialysis therapy,while the control group was provided with low-flux hemodialysis therapy.Renal function indexes,inflammatory factors and blood glucose were compared between the two groups.Results Compared with the control group,Ccr of the study group was significantly increased,BUN and Scr,TNF-αand IL-6 and IL-18,FPG and 2hPG,FINS and HbA1c were significantly decreased(P<0.05).Conclusion High throughput hemodialysis therapy can improve renal function,reduce inflammation and reduce high blood glucose level in the treatment of diabetic nephropathy patients,and is worthy of clinical application.

关 键 词：高通量血液透析 糖尿病肾病 肌酐清除率 炎性因子 

分 类 号：R692.5[医药卫生—泌尿科学] R587.2[医药卫生—外科学]