四季更替对宿州地区鲜胚移植临床结局的影响  

Effect of Seasonal Changes for Clinical Outcomes of Fresh Embryo Transplantation in Suzhou Area

作　　者：童旭 张丹丹 沈澍[1,2] TONG Xu;ZHANG Dandan;SHEN Shu(Department of Reproductive Medicine,Wanbei Coal and Electricity Group General Hospital,Suzhou,Anhui 234000;Suzhou City Key Laboratory of Reproductive Medicine and Embryology,Suzhou,Anhui 234000)

机构地区：[1]皖北煤电集团总医院生殖医学科,安徽宿州234000 [2]宿州市生殖医学与胚胎重点实验室,安徽宿州234000

出　　处：《智慧健康》2024年第20期28-31,共4页Smart Healthcare

摘　　要：目的探究四季更替对宿州地区鲜胚移植临床结局的影响。方法将2018年1月—2020年12月本院收治的543例进行鲜胚移植的患者纳入研究。根据移植时所处的季节分为春季组(147例)、夏季组(169例)、秋季组(130例)、冬季组(97例)四组,比较各组患者基本资料、获卵、受精和胚胎发育及妊娠诊断相关指标。结果四组患者的年龄、身体质量指数、不孕年限、LH与E2基础水平以及促性腺激素(Gn)天数和总量相似,差异无统计学意义(P>0.05);四组患者的获卵数、卵成熟和受精个数、2PN及其卵裂数、可利用胚胎数和优质胚胎数水平无显著差异、无统计学意义(P>0.05),仅可移植胚胎数差异有统计学意义(P<0.05);四组患者的卵母细胞成熟率、受精率、可利用胚胎率和优质胚胎率水平无差异无统计学意义(P>0.05),2PN卵裂率和囊胚率差异有统计学意义(P<0.05)。此外,各组患者的胚胎种植率、临床妊娠率、早期流产率、异位妊娠率差异无统计学意义(P>0.05)。结论四季更替不会影响宿州地区鲜胚移植的临床结局。Objective To investigate effect of seasonal changes for clinical outcomes of fresh embryo transplantation in Suzhou area.Methods The paper included 543 patients with fresh embryo transplantation in our hospital from January 2018 to December 2020 for study,and divided into four groups according to the season of transplantation:spring(147 cases),summer(169 cases),autumn(130 cases)and winter(97 cases).Basic information,egg retrieval,fertilization,embryo development and pregnancy diagnostic indicators were compared between groups.Results Age,body mass index,infertility years,LH and E2 basal levels,Gn days and total amount were similar among four groups,difference was not statistically significant(P>0.05).There was no significant difference in number of eggs retrieval,number of egg maturation and fertilization,2PN and cleavage number,number of available embryos and high-quality embryos among four groups,withour statistical significance(P>0.05).Only difference of number of transferable embryos was statistically significant(P<0.05).There was no significant difference in oocyte maturation rate,fertilization rate,available embryo rate and quality embryo rate among four groups,withour statistical significance(P>0.05).There was significant difference in 2PN cleavage rate and blastocyst rate among four groups(P<0.05).In addition,difference in embryo implantation rate,clinical pregnancy rate,early abortion rate and ectopic pregnancy rate showed no statistical significance among four groups(P>0.05).Conclusion Seasonal changes do not affect clinical outcomes of fresh embryo transplantation in Suzhou area.

关 键 词：四季更替 鲜胚移植 临床结局 

分 类 号：R714.8[医药卫生—妇产科学]