川芎祛瘀汤对关节镜下肩袖修补术后患者活动障碍和疼痛的影响  

Effect of Chuanxiong Quyu Decoction on Movement Disorders and Pain in Patients After Arthroscopic Rotator Cuff Repair Surgery

作　　者：杜江[1] 宁凡友 赵子龙 王晓琼[3] DU Jiang;NING Fan-you;ZHAO Zi-long;WANG Xiao-qiong(The First Department of Orthopedics and Traumatology,Anyang Hospital of Traditional Chinese Medicine,Henan Province,Anyang Henan 455000;The Third Department of Shoulder and Elbow Surgery,Luoyang Orthopedics-Traumatology Hospital of Henan Province(Henan Provincial Orthopedic Hospital),Zhengzhou Henan 450000;National Medicine Hall,Anyang Hospital of Traditional Chinese Medicine,Henan Province,Anyang Henan 455000)

机构地区：[1]河南省安阳市中医院骨伤一科,河南安阳455000 [2]河南省洛阳正骨医院(河南省骨科医院)肩肘外三科,河南郑州450000 [3]河南省安阳市中医院国医堂,河南安阳455000

出　　处：《世界中西医结合杂志》2024年第10期2046-2050,2055,共6页World Journal of Integrated Traditional and Western Medicine

基　　金：河南省中医药科学研究专项课题(2023ZY2120);河南省第二批中医药青苗人才培养项目(豫卫中医函[2021]16号)。

摘　　要：目的观察川芎祛瘀汤对关节镜下肩袖修补术后患者活动障碍和疼痛的影响。方法选取2020年1月—2023年1月期间安阳市中医院收治的90例肩袖损伤行关节镜下肩袖修补术患者,采用随机数字表法分为对照组和观察组,每组各45例。术后对照组予常规治疗及护理,观察组加用川芎祛瘀汤治疗。连续治疗4周。观察比较两组患者术前后疼痛、肩关节功能、肩关节活动情况、白细胞介素-6(Interleukin-6,IL-6)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)及血管内皮生长因子(Vascular endothelial growth factor,VEGF)表达。结果术后2、4周两组患者VAS评分均较术前降低,差异有统计学意义(P<0.05);且观察组术后2、4周VAS评分均明显低于对照组,差异有统计学意义(P<0.05)。术后4、8周两组患者UCLA评分及Constant-Murley评分均较术前明显下降,差异有统计学意义(P<0.05);且观察组术后4、8周UCLA评分及Constant-Murley评分均明显低于对照组,差异有统计学意义(P<0.05)。术后8周两组患者肩关节活动度均较术前明显升高,差异有统计学意义(P<0.05);且观察组肩关节活动度明显高于对照组,差异有统计学意义(P<0.05)。术后4周两组患者IL-6、TNF-α表达均较术前明显降低,VEGF表达均较治疗前明显升高,差异有统计学意义(P<0.05);且观察组IL-6、TNF-α含量均明显低于对照组,VEGF明显高于对照组,差异有统计学意义(P<0.05)。结论川芎祛瘀汤能有效缓解关节镜下肩袖修补术后患者疼痛,促进术后患者肩关节功能恢复,改善其关节活动,有效抑制炎症反应,促进血管再生,改善局部微循环。Objective To observe the effect of Chuanxiong Quyu decoction on movement disorders and pain in patients after arthroscopic rotator cuff repair surgery.Methods A total of 90 patients with rotator cuff injuries who underwent arthroscopic rotator cuff repair surgery at Anyang Hospital of Traditional Chinese Medicine from January 2020 to January 2023 were selected.They were divided into a control group and an observation group according to the random number table method,with 45 patients in each group.The control group received conventional treatment and care after surgery,while the observation was additionally treated with Chuanxiong Quyu decoction for 4 consecutive weeks.Pain levels,shoulder joint function,range of motion,and the expression of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),and vascular endothelial growth factor(VEGF)were compared before and after surgery in both groups.Results At 2 and 4 weeks post-surgery,visual analog scale(VAS)scores in both groups were significantly lower than before surgery,with statistically significant differences(P<0.05);the observation group showed significantly lower VAS scores than the control group,with statistically significant differences(P<0.05).At 4 and 8 weeks post-surgery,UCLA and Constant-Murley scores significantly improved in both groups compared to pre-surgery levels,with statistically significant differences(P<0.05);the observation group showed significantly better scores than the control group,with statistically significant differences(P<0.05).At 8 weeks post-surgery,shoulder joint range of motion significantly increased in both groups compared to pre-surgery levels,with statistically significant differences(P<0.05);the observation group demonstrated a significantly greater increase than the control group,with statistically significant differences(P<0.05).At 4 weeks post-surgery,IL-6 and TNF-αsignificantly decreased,while VEGF levels significantly increased in both groups compared to pre-treatment levels,with statistically significant differences(P<0.0

关 键 词：川芎祛瘀汤 肩袖损伤 关节镜 肩袖修补术 活动障碍 疼痛 

分 类 号：R684[医药卫生—骨科学]