创伤后脓毒症早期预警的研究进展  

Research progress on early warning of sepsis afteRtrauma

作　　者：勾燚 杨万朋 施玉茹 刘良伟 冯珂[1] Gou Yi;Yang Wanpeng;Shi Yuru;Liu Liangwei;Feng Ke(Department of Emergency,General Hospital of Ningxia Medical University,Yinchuan 750000,China;The First Clinical Medical College,Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院急诊科,银川750000 [2]宁夏医科大学第一临床医学院,银川750004

出　　处：《创伤外科杂志》2024年第11期869-873,共5页Journal of Traumatic Surgery

基　　金：宁夏回族自治区重点研发计划项目(2022BEG02049);宁夏回族自治区自然科学基金重点项目(2023AAC02068)。

摘　　要：脓毒症是由于宿主对感染的反应失调导致的危及生命的器官功能障碍,创伤患者脓毒症发生风险较高。早期预警是创伤后脓毒症防治的关键,目前相关研究取得了显著进展。本文重点从利用常规临床数据进行危险因素分析和预测模型建立、血浆生物标志物、差异性代谢物和易感基因筛查等方面进行综述,旨在为创伤后脓毒症的早期预警研究提供思路。Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection.Trauma patients are at a high risk of sepsis and early warning is crucial foRits prevention and treatment.Significant progress has been made in related research.Studies focusing on the analysis of risk factors and the establishment of predictive models using routine clinical data,plasma biomarkers,and screening of differential metabolites and susceptibility genes are comprehensively reviewed,to provide insights foRearly warning research on sepsis afteRtrauma.

关 键 词：脓毒症 创伤 早期预警 研究进展 

分 类 号：R459.7[医药卫生—急诊医学]