人工破膜孕妇抗生素应用时机的临床效果观察  

Clinical observation on the timing of antibiotic application in pregnant women with artificial mem-brane 1rupture

作　　者：胡娟娟 Hu Juanjuan(Ganzhou Maternal and Child Health Hospital,Ganzhou,Jiangxi 341000)

机构地区：[1]赣州市妇幼保健院,江西赣州341000

出　　处：《辽宁医学杂志》2024年第5期12-15,共4页Medical Journal of Liaoning

基　　金：赣州市卫生健康委科研计划项目,编号:2023-2-049。

摘　　要：目的 观察人工破膜孕妇抗生素应用时机的临床效果。方法 选择2021年1月—2022年12月于赣州市妇幼保健院行人工破膜孕妇82例,按随机数字表法将其分为两组,各41例。两组孕妇均行人工破膜处理,对照组在行人工破膜6h后使用抗生素预防感染治疗,观察组在行人工破膜即刻使用抗生素预防感染治疗。比较两组的不良分娩结局与分娩方式。结果 观察组的宫内感染率(9.76%)低于对照组(29.27%),差异有统计学意义(P<0.05);两组的产后出血率、新生儿窒息率比较,差异无统计学意义(P>0.05);观察组剖宫产率(9.76%)低于对照组(29.27%),自然分娩率(78.05%)高于对照组(56.10%),差异有统计学意义(P<0.05);两组阴道助产率比较,差异无统计学意义(P>0.05)。结论 孕妇人工破膜后即刻使用抗生素预防感染治疗效果良好,有利于降低宫内感染率及剖宫产率,提高自然分娩成功率,能够为临床人工破膜孕妇的抗感染治疗提供指导。Objective To observe the clinical effect of the timing of antibiotic application in pregnant women with artifi-cial membrane rupture.Methods 82 pregnant women who underwent artificial membrane rupture at Ganzhou Maternal and Child Health Hospital from January 2021 to December 2022 were selected and randomly divided into two groups,with 41 cases in each group.Both groups underwent artificial membrane rupture treatment.The control group received antibiotic prophylactic treatment 6 hours after artificial membrane rupture,while the observation group received antibiotic prophylactic treatment im-mediately after artificial membrane rupture.Compare the adverse pregnancy outcomes and delivery methods between the two groups.Results The intrauterine infection rate in the observation group(9.76%)was lower than that in the control group(29.27%),with a statistically significant difference(P<0.05);There was no statistically significant difference in the rates of postpartum hemorrhage and neonatal asphyxia between the two groups(P>0.05);The cesarean section rate in the observation group(9.76%)was lower than that in the control group(29.27%),and the natural delivery rate(78.05%)was higher than that in the control group(56.10%),with a statistically significant difference(P<0.05);There was no statistically significant difference in vaginal delivery rates between the two groups(P>0.05).Conclusion Immediate use of antibiotics for infection prevention and treatment in pregnant women after artificial rupture of membranes is effective,which is beneficial for reducing the rate of intrauterine infection and cesarean section,improving the success rate of natural delivery,and providing guidance for anti infection treatment in clinical artificial rupture of membranes for pregnant women.

关 键 词：人工破膜孕妇 抗生素应用时机 不良妊娠结局 分娩方式 

分 类 号：R714.2[医药卫生—妇产科学]