蒙药巴特尔-7治疗肠炎相关性脓毒症病例观察  

Observation on the treatment of enterititis-related sepsis with Mongolian medicine Bateer-7

作　　者：青格勒 包巴根那 乌云必力格 Qinggele;BAO Bagenna;Wuyunbilige(International Mongolian Hospital of Inner Mongolia,Inner Mongolia,Hohhot 010065)

机构地区：[1]内蒙古自治区国际蒙医医院,内蒙古呼和浩特010065

出　　处：《中国民族医药杂志》2024年第9期5-8,共4页Journal of Medicine and Pharmacy of Chinese Minorities

基　　金：内蒙古自治区公立医院高水平临床专科发展科技项目:蒙药巴特尔-7治疗肠炎相关性脓毒症的临床疗效及作用机制研究,项目编号:2023SGGZ137。

摘　　要：目的:通过使用蒙药巴特尔-7治疗肠炎相关性脓毒症患者,观察巴特尔-7临床疗效。方法:选取内蒙古自治区国际蒙医医院急诊与重症医学科2022年01月—2023年12月收治的40例肠炎相关性脓毒症患者作为研究对象,将患者以随机数字表法分为对照组和实验组,每组20例。对照组给予危重症常规内科治疗,实验组给予重症常规内科治疗的同时每日口服或鼻饲管给药巴特尔-7(15粒/2次),治疗7天为一个疗程。比较两组患者治疗前后白细胞计数、C-反应蛋白、降钙素原、乳酸等,记录SOFA评分、APECHE-II评分;蒙医症状评分;观察记录患者呕吐情况、肠鸣音、大便次数、腹痛、腹胀情况,同时记录蒙医脉、舌、尿等辨证诊察指标。进行用药安全性检查:(1)心电图。(2)全身反应(随时记录):应激性反应、过敏、并发症等。(3)血常规、尿常规、肝功能10项、肾功能5项、电解质、凝血功能、便常等。结果:实验组对比对照组白细胞计数;C-反应蛋白;降钙素原;乳酸有所下降(P<0.05),SOFA评分、APECHE-II评分无明显差异(P>0.05),实验组对比对照组体温下降、呕吐次数减少、大便次数减少、肚痛、腹胀情况改善,实验组蒙医脉象为实而紧,对照组蒙医脉象洪而紧、实验组蒙医舌诊为舌黄,苔厚,对照组蒙医舌诊为舌黄,苔厚黏腻、蒙医尿诊实验组和对照组均为黄色、味浓、泡沫色青且小。安全性指标无明显差异(P>0.05)。结论:蒙药巴特尔-7治疗肠炎相关性脓毒症能有效降低血清炎症指标,改善SOFA评分、APECHE-II评分、蒙医症状评分,减轻呕吐、肚痛、腹胀、腹泻情况,临床用药较为安全,可以在临床应用。Objective:To observe the clinical efficacy of Mongolian medicine Bateer-7 in the treatment of enterititisassociated sepsis.Methods:A total of 40 patients with enteritise-related sepsis admitted to the Department of Emergency and Critical Care Medicine of the International Mongolian Hospital of Inner Mongolia Autonomous Region from January 2022 to December 2023 were selected as the research objects,and the patients were divided into control group and experimental group by random number table method,with 20 cases in each group.The control group was given conventional medical treatment for critical cases,and the experimental group was given conventional medical treatment for severe cases,while Bateer-7 was given orally or nasogastric tube daily(15 capsules/2 times)for a course of treatment for 7 days.White blood cell count,C-reactive protein,procalcitonin and lactic acid were compared between the two groups before and after treatment.SOFA score and APECHE-II score were recorded.Mongolian medicine symptom score;Vomiting,bowel sound,frequency of stool,abdominal pain and abdominal distension were observed and recorded.Meanwhile,dialectical examination indexes such as pulse,tongue and urine were recorded.Drug safety check:①electrocardiogram.②Systemic reactions(recorded at any time):stress reactions,allergies,complications,etc.③Blood routine,urine routine,liver function 10 items,kidney function 5 items,electrolyte,coagulation function,stool,etc.Results:The leukocyte count in the experimental group was compared with that in the control group.C-reactive protein;Procalcitonin;Lactic acid decreased(P<0.05),SOFA score and APECHE-II score had no significant difference(P>0.05),the experimental group compared with the control group decreased body temperature,reduced vomiting frequency,reduced stool frequency,abdominal pain,abdominal distension improved,the experimental group Mongolian medicine pulse was solid and tight,the control group Mongolian medicine pulse was flood and tight,the experimental Mongolian medicine tongue

关 键 词：脓毒症 肠炎相关性脓毒症 蒙医药 巴特尔-7 

分 类 号：R29[医药卫生—民族医学]