补阳还五汤治疗退行性脊柱术后残留症状效果观察  

Clinical observation on Buyang Huanwu Decoction in treatment of residual symptoms after degenerative spine surgery

作　　者：李翩 蔡子鸣 梁金柱 阮烨 林淑惠 林文平 LI Pian;CAI Zi-ming;LIANG Jin-zhu;RUAN Ye;LIN Shu-hui;LIN Wen-ping(Guangzhou University of ChineseMedicine,Guangzhou 510006;Guangdong Provincial Shenzhen Pingle Orthopedic Hospital/Guangdong Provincial Shenzhen Pingshan District Hospital of TCM,Shenzhen 518010)

机构地区：[1]广州中医药大学,广东广州510006 [2]广东省深圳平乐骨伤科医院/广东省深圳市坪山区中医院,广东深圳518010

出　　处：《湖北中医药大学学报》2024年第5期82-84,共3页Journal of Hubei University of Chinese Medicine

基　　金：广东省自然科学基金面上项目(项目编号:2021A1515010722)。

摘　　要：目的 观察补阳还五汤治疗退行性脊柱术后残留症状的效果。方法 将我院80例退行性脊柱术后残留症状患者随机分为对照组与观察组各40例。对照组采用常规治疗,观察组采用补阳还五汤联合常规疗法治疗。比较两组优良率;疼痛视觉模拟评分法(VAS)、日本骨科学会评分(JOA)、Oswestry功能障碍指数(ODI)、美国脊髓损伤学会(ASIA)感觉和运动评分;肿瘤坏死因子-α(TNF-α)、白介素-1β(IL-1β),测量直腿抬高试验角度(LG)、腰椎整体活动度(ROM);检测活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)。结果 治疗后,观察组优良率高于对照组(P<0.05);两组VAS、ODI评分低于治疗前,JOA、ASIA感觉和运动评分高于治疗前,观察组VAS、ODI评分低于对照组,JO A、ASIA感觉和运动评分高于对照组(P<0.05);两组TNF-α、IL-1β水平低于治疗前,观察组TNF-α、IL-1β水平低于对照组(P<0.05);两组LG、ROM高于治疗前,观察组LG、ROM高于对照组(P<0.05);两组APTT、PT低于治疗前,观察组APTT、PT高于对照组(P<0.05)。结论 补阳还五汤治疗退行性脊柱术后残留症状的效果好,减轻疼痛,改善功能,提高感觉和运动功能,降低炎性指标,扩大关节活动度,改善血液高凝。Objective To observe the effect of Buyang Huanwu Decoction in treatment of residual symptoms after degenerative spine surgery.Methods Eighty patients with residual symptoms after degenerative spine surgery were randomly divided into control group and observation group with 40 cases in each group.Control group was treated with conventional treatment,and observation group was treated with Buyang Huanwu Decoction on the basis of control group.The excellent rates of the two groups were compared after treatment;the scores of Visual Analogue Scale(VAS),Japanese Orthopaedic Association score(JOA),Oswestry Dysfunction Index(ODI),American Society of Spinal Cord Injury(ASIA)sensory,and motor,tumor necrosis factor-α(TNF-α)and interleukin-1β(IL-1β)levels,straight leg raise test(LG)angle,overall range of motion(ROM)of the lumbar spine,activated partial thromboplastin time(APTT)and prothrombin time(PT)of the two groups were compared before and after treatment.Results After treatment,the excellent rate of observation group was higher than that of control group(P<0.05);VAS and ODI scores in both groups were lower than those before treatment,while the sensory and motor scores of JOA and ASIA were higher,and the above indicators in observation group were superior to those in control group(P<0.05);the levels of TNF-αand IL-1βin both groups were lower than those before treatment,and were lower in observation group than those in control group(P<0.05);LG and ROM in both groups were higher than those before treatment,and were higher in observation group than those in control group(P<0.05);APTT and PT of both groups were lower than those before treatment,and were higher in observation group than control group(P<0.05).Conclusion Buyang Huanwu Decoction has a good effect in treatment of residual symptoms after degenerative spine surgery,reducing pain,improving function,improving sensory and motor function,reducing inflammatory indicators,expanding joint mobility,and improving blood hypercoagulability.

关 键 词：退行性脊柱术 残留症状 补阳还五汤 

分 类 号：R274.9[医药卫生—中西医结合]