Food restriction heals darkness-related second brain inflammation  

作　　者：Vinicius Kannen 

机构地区：[1]University of Toronto,Department of Pharmacology and Toxicology,1 King’s College Cir,Toronto,ON,M5S 1A8,Canada

出　　处：《Cellular & Molecular Immunology》2024年第8期938-940,共3页中国免疫学杂志（英文版）

摘　　要：In the central nervous system(CNS),the suprachiasmatic nucleus(SCN)integrates signals from the body with light cues(Zeitgeber),which specialized retinal cells recognize(Fig.1A)[1].This allows for the coordination of daily physiological and behavioral rhythms in roughly a 24-hour cycle[2].While light serves as the primary signal for synchronizing the body with the external environment,constant exposure to light can disrupt the circadian system.Shift workers,for example,are a group at risk for experiencing such disruptions in both central and peripheral circadian rhythms of clock genes.While light strongly disrupts the sleep-wake cycle due to SCN arrhythmicity,constant darkness alters this system with minimal environmental interference and provides a model for studying its intrinsic properties[1-3].

关 键 词：SYSTEM specialized LIGHT 

分 类 号：R515.2[医药卫生—内科学]