Advances in micropillar arrays in cellular biomechanics detectionand tissue engineering  

作　　者：XUELING HE LINLU JIN YIXUE QIN JIAN ZHONG ZHI OUYANG YE ZENG 

机构地区：[1]Institute of Biomedical Engineering,West China School of Basic Medical Sciences&Forensic Medicine,Sichuan University,Chengdu,610041,China

出　　处：《BIOCELL》2024年第11期1521-1529,共9页生物细胞（英文）

基　　金：Supported by the National Natural Science Foundation of China(No.12272246);the Key Research and Development Projects in Sichuan Province(No.2023YFS0075).

摘　　要：Cellular biomechanical features contributed to the occurrence and development of various physiological andpathological phenomena. Micropillar arrays have emerged as an important tool for both the assessment andmanipulation of cellular biomechanical characteristics. This comprehensive review provides an in-depthunderstanding of the fabrication methodologies of micropillar arrays and their applications in deciphering and finetuning cellular biomechanical properties and the innovative experimental platforms including organ-on-a-chip andorganoids-on-a-chip. This review provides novel insights into the potential of micropillar technology, poised toupdate the landscape of stem cell research and tissue engineering.

关 键 词：Micropillar Cellular biomechanics Stem cell LAB-ON-A-CHIP Organoid-on-a-chip 

分 类 号：R318[医药卫生—生物医学工程]