晶状体混浊放射工作人员遗传指标及职业特征分析  

Analysis of cytogenetic indexes and occupational characteristics of radiation workers with lens opacity

作　　者：边阳甫[1] 钟皓成[1] 金琪 潘萍萍 Bian Yangfu;Zhong Haocheng;Jin Qi;Pan Pingping(Occupational Disease Departent of Hangzhou Hospital for the Prevention and Treatment of Occupational Disease,Hangzhou 310014,China)

机构地区：[1]杭州市职业病防治院职业病科,杭州310014

出　　处：《中华劳动卫生职业病杂志》2024年第10期743-745,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：浙江省医药卫生科技计划(2020KY783);杭州市医药卫生科技项目(20211231Y083)。

摘　　要：目的了解不同工龄、年龄及工种放射工作人员晶状体混浊情况,分析辐射性晶状体混浊放射工作人员的微核及染色体特点。方法于2022年1月,选取2014年3月至2021年12月在杭州市职业病防治院进行放射职业健康检查且检查出晶状体混浊的400名放射工作人员为研究对象。分析不同工龄、工种、年龄等放射工作人员眼晶状体混浊比例、外周血淋巴细胞微核异常率及染色体畸变率之间的差异。结果与工龄<20年放射工作人员微核异常率(0.18‰)和染色体畸变率(0.31%)比较,工龄≥20年放射工作人员外周血淋巴细胞微核异常率(0.59‰)和染色体畸变率(2.67%)更高,差异均有统计学意义(P<0.05);介入放射人员微核率(0.32‰)及染色体畸变异常率(0.57%)高于牙科放射人员(0.12‰和0.19%)和诊断放射人员(0.05‰和0.12%),差异均有统计学意义(χ^(2)=23.98、6.72,P<0.05)。结论介入放射人员微核异常率及染色体畸变率高于牙科放射、传统诊断放射人员,放射工作人员必须做好个人防护,定期进行放射职业健康检查。ObjectiveTo analyse the characteristics of micronuclus and chromosomal aberrations and the lens opacity in different working years,ages and work type of radiation workers with lens opacity.MethodsIn January 2022,we selected 400 radiation workers with lens opacity who had undergone occupational health examination in Hangzhou Hospital for the Prevention and Treatment of Occupational Disease from March 2014 to December 2021 as research objects.To analyze the differences of micronucleus,chromosome aberration and the lens opacification rates of different length of service,type of work,age radiologic workers.ResultsThe results showed that radiation the micronucleus abnormality(0.59‰)and chromosome aberration(2.67%)in peripheral blood in workers who served more than 20 years were significantly higher than that of micronucleus abnormality(0.18‰)and chromosome aberration(0.31%)in workers served less than 20 years,the differences were statistically significant(P<0.05).The micronucleus abnormality(0.32‰)and chromosome aberration(0.57%)in the interventionist were higher than oral radiation workers(0.12‰and 0.19%)and diagnostic radiologist(0.05‰and 0.12%),the differences were statistically signcficant(χ^(2)=23.98,6.72,P<0.05).ConclusionThe rates of micronucleus and chromosome aberration of the interventionaist are higher than oral radiation workers and the traditional radiologist.Workers engaged in radiation should improve personal protection and undertake regular occupational health examinations.

关 键 词：放射 染色体 微核 淋巴细胞 医疗机构 细胞遗传指标 职业特征 

分 类 号：R148[医药卫生—公共卫生与预防医学]