冠脉微循环障碍临床诊疗研究进展  

Progress in Clinical Diagnosis and Treatment of Coronary Microvascular Disease

作　　者：蒋虎刚 刘爱(综述) 李应东(审校)[1] JIANG Hu-gang;LIU Ai;LI Ying-dong(Department of Integrative Medicine,Gansu University of Chinese Medicine,Lanzhou 730000,China)

机构地区：[1]甘肃中医药大学,兰州730000

出　　处：《微循环学杂志》2024年第4期99-104,共6页Chinese Journal of Microcirculation

基　　金：国家自然科学基金(82374279);甘肃省青年科技基金资助项目(23JRRA1217);2021年度“双一流”科研重点项目(GSSYLXM-05-ZXYJH-11)。

摘　　要：冠脉微循环障碍(CMVD)是心血管领域的研究热点,本文通过总结高血压、冠心病和雌激素水平降低等与CMVD发病的关系,微血管神经调节、体液调节以及血管结构异常诱导CMVD的机制,侵入性和非侵入性的检查手段的类型及其各自的优势与不足,抗心肌缺血、改善心肌能量代谢、抗炎、抗氧化等药物在CMVD防治中的应用等,对CMVD的病因、发病机制、诊断技术以及药物治疗的文献进行综述,以期为CMVD的诊断治疗提供新视角。Coronary microvascular disease(CMVD)is a hot research topic in the field of cardiovascular.This article summarizes the hypertension,coronary heart disease(CHD)and low estrogen levels to the incidence of CMVD,and the effects of microvascular nervous regulation,humoral regulation and abnormal vascular structures in the mechanism of inducing CMVD,the types of invasive and non-invasive examination methods for the diagnosis of CMVD,and their advantages and disadvantages,respectively.Finally,the application of anti-myocardial ischemia,improvement of myocardial energy metabolism,anti-inflammatory,antioxidant and other drugs in the prevention and treatment of CMVD were reviewed.The etiology,pathogenesis,diagnostic techniques and drug therapy of CMVD were reviewed in order to provide a new perspective for the diagnosis and treatment of CMVD.

关 键 词：冠脉微循环障碍 危险因素 诊断技术 药物治疗 

分 类 号：R541.4[医药卫生—心血管疾病]